Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
17q21	NCIT_C13481	[A chromosome band present on 17q]
Monoclonal Antibody 96.5 F(ab)	NCIT_C29206	[A monovalent Fab fragment of the mouse monoclonal antibody (MoAb) 96.5, raised against an epitope from human melanoma-associated cell surface marker p97. MoAb 96.5 Fab fragments are composed of one constant and one variable domain of each of the heavy and the light chain which together shape the antigen binding site at the amino terminal end of the monomer. MoAb 96.5 Fab fragments are obtained through papain digestion in the presence of cysteine. The advantage of using MoAb 96.5 Fab fragments over whole antibodies is that they have reduced immunogenicity, better penetration of tissues, rapid clearance from the body and that they do not induce precipitation.]
Suspected Source Case	NCIT_C132452	[An individual who is believed to have likely transmitted a disease to another individual.]
STIM1 Gene	NCIT_C20862	[This gene plays a role in hematopoiesis and may play a role in malignant development.]
Rhabdoid Tumor	NCIT_C3808	[An aggressive malignant embryonal neoplasm usually occurring during childhood. It is characterized by the presence of large cells with abundant cytoplasm, large eccentric nucleus, and a prominent nucleolus and it is associated with abnormalities of chromosome 22. It can arise from the central nervous system, kidney, and the soft tissues. The prognosis is poor.]
Glial Fibrillary Acidic Protein	NCIT_C68804	[Glial fibrillary acidic protein (432 aa, ~50 kDa) is encoded by the human GFAP gene. This protein may be involved in both neuronal maintenance and astrocyte morphology and motility.]
MOAB B-3-CHX-A-DTPA	NCIT_C29207	[A monoclonal antibody B3, recognizing the tumor-associated Lewis Y antigen, is conjugated to a backbone-substituted derivative of DTPA, 2-(p-isothiocyanatobenzyl)-cyclohexyl-diethylenetriaminepentaacetic acid (CHX-A DTPA). DTPA is a bifunctional chelating agent thereby allowing for the binding of radioisotopes to the immunoconjugate.]
Forced Expiratory Volume in 3 Seconds	NCIT_C132453	[The volume exhaled during the first three seconds of a forced expiratory maneuver that is started from the level of total lung capacity.]
Mitogen	NCIT_C660	[A soluble substance, usually a protein, that induces mitosis in resting cells, thereby causing cell proliferation.]
Monoclonal Antibody B6.2 F(ab')	NCIT_C29208	[The Fab fragment of the B6.2 monoclonal antibody that recognizes the B6.2 antigen, a 90,000-d glycoprotein found on the surface of human mammary tumors. MOAB B6.2 F (AB') binds to breast carcinoma cells and has potential use in immunodiagnostic imaging and the immunotherapy of breast cancer. MOAB B6.2 F (AB') exhibits improved tumor localization and a shorter half-life than the complete antibody. (NCI04)]
PCWG Scher Prostate Cancer 2016 Oncology Response Criteria	NCIT_C132454
Long-Term Care Nursing	NCIT_C20870	[Professional nursing care provided in a long-term care/nursing facility to residents unable to provide for themselves a safe and adequate level of care.]
Australia-Modified Karnofsky Performance Status 40	NCIT_C107490	[In bed more than 50% of the time.]
Karnofsky Performance Status	NCIT_C28013	[An index designed for classifying patients 16 years of age or older by their functional impairment.]
Australia-Modified Karnofsky Performance Status 30	NCIT_C107491	[Almost completely bedfast.]
Australia-Modified Karnofsky Performance Status 20	NCIT_C107492	[Totally bedfast and requiring extensive nursing care by professionals and/or family.]
Australia-Modified Karnofsky Performance Status 10	NCIT_C107493	[Comatose or barely arousable.]
Auto-triggered	NCIT_C107494	[Activation of a system without outside interference.]
Anti-Drug Antibody	NCIT_C107495	[An antibody that binds to an administered drug. Expression of these antibodies is thought to be induced by (repeated) drug administration.]
Neutralizing Anti-Drug Antibody	NCIT_C107496	[An antibody that binds to an administered drug and inhibits the biological activity of that drug. Expression of these antibodies is thought to be induced by (repeated) drug administration.]