Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Regeneration	NCIT_C17083	[Reproduction or reconstitution of a lost or injured part. (NCI)]
Monoclonal Antibody CEM-231	NCIT_C29217	[A monoclonal antibody directed against carcinoembryonic antigen (CEA) which is expressed by most gastrointestinal carcinomas and by some breast, lung and ovarian carcinomas. (NCI04)]
Anti-CEA Antibody	NCIT_C2456	[Any antibody against the tumor associated antigen carcinoembryonic antigen (CEA; CEACAM5), with potential antineoplastic activity. The CEA antigen is overexpressed in certain types of cancer cells.]
Nivolumab	NCIT_C68814	[A fully human immunoglobulin (Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1 (PD-1, PCD-1) with immune checkpoint inhibitory and antineoplastic activities. Upon administration, nivolumab binds to and blocks the activation of PD-1, an immunoglobulin superfamily (IgSF) transmembrane protein, by its ligands programmed cell death ligand 1 (PD-L1), which is overexpressed on certain cancer cells, and programmed cell death ligand 2 (PD-L2), which is primarily expressed on antigen-presenting cells (APCs). This results in the activation of T-cells and cell-mediated immune responses against tumor cells. Activated PD-1 negatively regulates T-cell activation and plays a key role in tumor evasion from host immunity.]
Number of Bone Lesions	NCIT_C132463	[A measurement of the total number of bone tumors.]
GPR39 Gene	NCIT_C20873	[This gene is involved in G protein-coupled receptor signal transduction and the regulation of growth factor release.]
Correct	NCIT_C68815	[Free from error; especially conforming to fact or truth.]
Number of New Bone Lesions	NCIT_C132464	[A measurement of the total number of bone tumors that have not been previously seen or characterized.]
Medical-Surgical Nursing	NCIT_C20874	[Medical-Surgical Nursing includes the provision of care to individuals who have a known or predicted physiological alteration. Working within an interdisciplinary team and guided by theory and research, medical-surgical nursing practice considers all influences on health status and the related social and behavioral problems arising because of the patient's physiological condition. Medical-surgical nursing is practiced in primary, acute, or long-term nursing care facilities. (from ANCC)]
Monoclonal Antibody COL-6	NCIT_C29219	[A recombinant immunoglobulin antibody directed against the tumor-associated carcinoembryonic antigen (CEA). CEA is a cell surface glycoprotein expressed at high levels in embryonic and fetal digestive epithelial tissue, breast carcinoma, and squamous cell carcinoma of the head and neck. Except for some reactivity to skin and gastric and colon mucosa, monoclonal antibody COL-6 does not appear to react with normal tissues.]
Sensitivity	NCIT_C68816	[A measure of the minimum change in an input signal that an instrument can detect.]
Two or More Persisting New Bone Lesions Indicator	NCIT_C132465	[An indication as to whether there are two or more bone tumors that have been previously seen or characterized.]
Monoclonal Antibody B6.2F(ab')2	NCIT_C29209	[A divalent F(ab)2 fragment of the monoclonal antibody (MoAb) B6.2 directed against the tumor-associated glycoprotein (TAG-90) found on the surface of primary and metastatic human mammary tumors.. MoAb B6.2 F(ab)2 fragments are obtained through pepsin digestion. The advantage of using MoAb B6.2 F(ab)2 fragments over whole antibodies is that they have reduced immunogenicity, better penetration of tissues, rapid clearance from the body and that they do not induce precipitation.]
Perianesthesia Nursing	NCIT_C20880	[Nursing care of the patient under anesthesia and in the immediate post-anesthesia period.]
Emergency Room Nursing	NCIT_C20881	[The nursing specialty concerned with the care of patients in the emergency room.]
PIK3CA NP_006209.2:p.E542X	NCIT_C107480	[A change in the amino acid residue at position 542 in the phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform protein where glutamic acid has been replaced by another amino acid.]
PIK3CA Protein Variant	NCIT_C98460	[A variation in the amino acid sequence for the phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform protein.]
PIK3CA NP_006209.2:p.E545X	NCIT_C107481	[A change in the amino acid residue at position 545 in the phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform protein where glutamic acid has been replaced by another amino acid.]
PIK3CA NP_006209.2:p.H1047X	NCIT_C107482	[A change in the amino acid residue at position 1047 in the phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform protein where histidine has been replaced by another amino acid.]
NRAS NP_002515.1:p.G12X	NCIT_C107483	[A change in the amino acid residue at position 12 in the GTPase NRas protein where glycine has been replaced by another amino acid.]