Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
NRAS Protein Variant	NCIT_C98439	[A variation in the amino acid sequence for the GTPase NRas protein.]
NRAS Exon 2 Mutation	NCIT_C135718	[A molecular genetic abnormality indicating the presence of a mutation in exon 2 of the NRAS gene.]
NRAS NP_002515.1:p.G13X	NCIT_C107484	[A change in the amino acid residue at position 13 in the GTPase NRas protein where glycine has been replaced by another amino acid.]
NRAS NP_002515.1:p.Q61X	NCIT_C107485	[A change in the amino acid residue at position 61 in the GTPase NRas protein where glutamine has been replaced by another amino acid.]
NRAS Exon 3 Mutation	NCIT_C135719	[A molecular genetic abnormality indicating the presence of a mutation in exon 3 of the NRAS gene.]
Tumor Microenvironment of Metastasis Density	NCIT_C107486	[A marker of potential sites for tumor metastasis, where separate histological stains for perivascular macrophages, blood vessel-resident endothelial cells and tumor cells are co-localized in a tissue section.]
Risk Marker	NCIT_C18493	[A characteristic that indicates the risk of developing a disease.]
Allelic Family	NCIT_C132433	[A subgroup of alleles of a polymorphic gene that may form clusters (e.g., phylogenetic) based on high sequence similarity, which may include either a shared single nucleotide polymorphism or a shared set of polymorphic sites.]
Amplicon Size	NCIT_C132434	[The number of base pairs present in an RNA or DNA sequence, which is the product of an amplification process.]
Accumulation Ratio AUC Over Dosing Interval Normalized by Dose	NCIT_C132435	[The area under the curve (AUCtau) at steady state divided by the area under the curve (AUCtau) over the initial dosing interval, each divided by the associated dose.]
Accumulation Ratio Area Under the Curve	NCIT_C102356	[The area under the curve (AUCTAU) at steady state divided by the area under the curve over the initial dosing interval.]
Accumulation Ratio AUC T1 to T2 Normalized by Dose	NCIT_C132436	[The area under the curve from T1 to T2 at steady state divided by the area under the curve from T1 to T2 during the initial dosing interval, each divided by the associated dose. (CDISC)]
Accumulation Ratio Cmax Normalized by Dose	NCIT_C132437	[The maximum concentration at steady state divided by the maximum concentration during the initial dosing interval, each divided by the associated dose. (CDISC)]
Accumulation Ratio Cmax	NCIT_C102357	[The maximum concentration at steady state divided by the maximum concentration during the initial dosing interval.]
Monoclonal Antibody 45-2D9	NCIT_C29220	[A synthetic antibody targeted against a cell surface glycoprotein (gp74) on a human c-Ha-ras oncogene transformed cell line. Monoclonal Antibody 45-2D9 also recognizes this epitope on certain human tumor cells. (NCI04)]
Accumulation Ratio Cmin Normalized by Dose	NCIT_C132438	[The minimum concentration at steady state divided by the minimum concentration during the initial dosing interval, each divided by the associated dose. (CDISC)]
Accumulation Ratio Cmin	NCIT_C102358	[The minimum concentration at steady state divided by the minimum concentration during the initial dosing interval.]
MOAB Colorectal Carcinoma	NCIT_C29221
Accumulation Ratio Ctrough Normalized by Dose	NCIT_C132439	[The trough concentration at steady state divided by the trough concentration during the initial dosing interval, each divided by the associated dose. (CDISC)]
Accumulation Ratio Ctrough	NCIT_C102426	[The trough concentration at steady state divided by the trough concentration during the initial dosing interval.]