Terminology Service for NFDI4Health
All terms in NCIT
| Label | Id | Description |
|---|---|---|
| Device Over The Counter Product Indicator | NCIT_C93805 | [Specifies whether a device is available over-the-counter.] |
| Microscopist 2 | NCIT_C132422 | [The second in a series of microscopists that are performing an assessment.] |
| CSNK2B Gene | NCIT_C107444 | [This gene plays a role in the regulation of casein kinase II.] |
| Microscopist 3 | NCIT_C132423 | [The third in a series of microscopists that are performing an assessment.] |
| CSNK2B wt Allele | NCIT_C107445 | [Human CSNK2B wild-type allele is located in the vicinity of 6p21.33 and is approximately 5 kb in length. This allele, which encodes casein kinase II subunit beta protein, is involved in the regulation of casein kinase II.] |
| Psyllium Husk | NCIT_C29250 | [The husk of the dried ripe seeds of the Plantago psyllium, P. Indica, P. Ovata, and P. Arenaria plants with laxative and cholesterol lowering activities. The husks contain mucilage that swells on exposure to water and provides an indigestible mucilaginous mass in the intestines, thereby causing lubrication, contraction of the smooth muscles of the intestinal walls, and thus stimulating bowel movement. Psyllium husk is rich in soluble fiber and has a cholesterol-lowering effect.] |
| Plant Part | NCIT_C79611 | [Any part of a plant that has not been processed further.] |
| Stage IV Bladder Cancer AJCC v6 | NCIT_C7900 | [Stage IV includes the following: T4b, N0, M0; Any T, N1, M0; Any T, N2 M0; Any T, N3 M0; Any T, Any N, M1. T4b: Tumor invades the pelvic wall, abdominal wall. N1: Metastasis in a single lymph node, 2 cm or less in greatest dimension. N2: Metastasis in a single lymph node, more than 2 cm but not more than 5 cm in greatest dimension; or multiple lymph nodes, none more than 5 cm in greatest dimension. N3: Metastasis in a lymph node more than 5 cm in greatest dimension. M1: Distant metastasis. (AJCC 6th Ed.) - 2003] |
| Optometrist | NCIT_C132424 | [A physician with a Doctor of Optometry degree (or analogous) that specializes in the diagnosis and treatment of eye disorders.] |
| Casein Kinase II Subunit Beta | NCIT_C107446 | [Casein kinase II subunit beta (215 aa, ~25 kDa) is encoded by the human CSNK2B gene. This protein plays a role in the regulation of casein kinase II.] |
| Metformin Hydrochloride | NCIT_C29251 | [The hydrochloride salt of the biguanide metformin with antihyperglycemic and potential antineoplastic activities. Metformin inhibits complex I (NADPH:ubiquinone oxidoreductase) of the mitochondrial respiratory chain, thereby increasing the cellular AMP to ATP ratio and leading to activation of AMP-activated protein kinase (AMPK) and regulating AMPK-mediated transcription of target genes. This eventually prevents hepatic gluconeogenesis, enhances insulin sensitivity and fatty acid oxidation and ultimately leads to a decrease in glucose levels. Metformin may exert antineoplastic effects through AMPK-mediated or AMPK-independent inhibition of mammalian target of rapamycin (mTOR), which is up-regulated in many cancer tissues. Furthermore, this agent also inhibits tumor cell migration and invasion by inhibiting matrix metalloproteinase-9 (MMP-9) expression which is mediated through the suppression of transcription activator protein-1 (AP-1) activation.] |
| Biguanide Antidiabetic Agent | NCIT_C98234 | [Any antidiabetic agent with the biguanide base structure or phenformin derivatives with antihyperglycemic activity. Biguanide antidiabetic agents activate AMP-activated protein kinase (AMPK) resulting in decreased glucose production in the liver, increased peripheral glucose uptake and improved utilization of glucose. Biguanide-based antidiabetic agents do not cause hypoglycemia. In addition, biguanide antidiabetics decrease absorption of glucose from the gastrointestinal tract.] |
| Stage I Testicular Cancer AJCC v6 and v7 | NCIT_C7901 | [Stage I includes: pT1-4, N0, M0, SX. pT1: Tumor limited to the testis and epididymis without vascular/lymphatic invasion; tumor may invade into the tunica albuginea but not the tunica vaginalis. pT2: Tumor limited to the testis and epididymis with vascular/lymphatic invasion, or tumor extending through the tunica albuginea with involvement of the tunica vaginalis. pT3: Tumor invades the spermatic cord with or without vascular/lymphatic invasion. pT4: Tumor invades the scrotum with or without vascular/lymphatic invasion. N0: No regional lymph node metastasis. M0: No distant metastasis. SX: Marker studies not available or not performed. (AJCC 6th and 7th eds.)] |
| Testicular Cancer by AJCC v6 and v7 Stage | NCIT_C140241 | [A term that refers to the staging of testicular cancer according to the American Joint Committee on Cancer, 6th and 7th editions.] |
| Rater 1 | NCIT_C132425 | [The first in a series of raters that are performing an assessment.] |
| GABRG1 Gene | NCIT_C107447 | [This gene is involved in the regulation of neurotransmission.] |
| Methocarbamol | NCIT_C29252 | [A carbamate with centrally acting muscle relaxant properties. Though the exact mechanism of action of methocarbamol was not established, it's postulated to be via a mechanism similar of carbamate, inhibition of acetylcholinesterase at synapses in the autonomic nervous system, neuromuscular junction, and central nervous system. Methocarbamol has no direct effect on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber.] |
| Rater 2 | NCIT_C132426 | [The second in a series of raters that are performing an assessment.] |
| GABRG1 wt Allele | NCIT_C107448 | [Human GABRG1 wild-type allele is located in the vicinity of 4p12 and is approximately 88 kb in length. This allele, which encodes gamma-aminobutyric acid receptor subunit gamma-1 protein, plays a role in mediating neuronal inhibition.] |
| 4p12 | NCIT_C25057 | [A chromosome band present on 4p] |