Terminology Service for NFDI4Health
All terms in NCIT
| Label | Id | Description |
|---|---|---|
| Methylcellulose | NCIT_C29253 | [The methyl ether of cellulose with laxative activity. Methylcellulose is not absorbed by the intestines and attracts large amounts of water into the colon, thereby increasing viscosity, producing a softer and bulkier stool and stimulating the constriction of intestinal smooth muscles.] |
| Fluorescent Spot Test | NCIT_C132427 | [A method to assess enzymatic activity in which a substrate reagent is incubated with a biological specimen and spotted on filter paper. The spots are then examined for fluorescence, which correlates with enzyme activity.] |
| Bioassay | NCIT_C16341 | [A laboratory test or analysis of the biological activity of a substance performed by studying its effect on an organism or in a test tube under controlled conditions.] |
| Gamma-Aminobutyric Acid Receptor Subunit Gamma-1 | NCIT_C107449 | [Gamma-aminobutyric acid receptor subunit gamma-1 (465 aa, ~54 kDa) is encoded by the human GABRG1 gene. This protein is involved in mediating neuronal inhibition.] |
| Metoprolol Succinate | NCIT_C29254 | [The succinate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol succinate antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thus decreasing sympathetic activation, including vasoconstriction, aldosterone secretion.] |
| Hillmen Color Chart | NCIT_C132428 | [A visual color scale created by Hillman et al in 2004 to enable standardization of urine color in the assessment of hemoglobinuria. (Hillmen P, Hall C, Marsh JC, Elebute M, Bombara MP, Petro BE, Cullen MJ, Richards SJ, Rollins SA, Mojcik CF, Rother RP. Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria. N Engl J Med. 2004 Feb 5;350(6):552-9.)] |
| Eye Examination | NCIT_C38060 | [A test performed by an ophthalmologist or optometrist assessing vision and ability to focus on and discern objects, as well as other tests and examinations pertaining to the eyes.] |
| Metoprolol Tartrate | NCIT_C29255 | [The tartrate salt form of metoprolol, a cardioselective competitive beta-1 adrenergic receptor antagonist with antihypertensive properties and devoid of intrinsic sympathomimetic activity. Metoprolol tartrate antagonizes beta 1-adrenergic receptors in the myocardium, thereby reducing the rate and force of myocardial contraction, and consequently a diminished cardiac output. This agent may also reduce the secretion of renin with subsequent reduction in levels of angiotensin II thus decreasing sympathetic activation, including vasoconstriction, aldosterone secretion.] |
| Enhanced Liver Fibrosis Score | NCIT_C132429 | [A scoring system for liver fibrosis developed by Lichtinghagen et al, based on an algorithm that takes into account tissue inhibitor of metalloproteinases 1 (TIMP-1), amino-terminal propeptide of type III procollagen (PIIINP) and hyaluronic acid (HA) levels. (Lichtinghagen R, Pietsch D, Bantel H, Manns MP, Brand K, Bahr MJ. The Enhanced Liver Fibrosis (ELF) score: normal values, influence factors and proposed cut-off values. J Hepatol. 2013 Aug;59(2):236-42.)] |
| International Steam Table Calorie | NCIT_C68853 | [A non-SI unit of energy defined by the Fifth International Conference on the Properties of Steam, London, 1956, as 1/860 x international watt hour or joule, or to 4.1868 joules exactly. According to the current national standard in the United States (IEEE/ASTM SI 10TM 2002. American National Standard for Use of the International System of Units (SI): The Modern Metric System, New York: IEEE, 2002) the calorie in any form is not to be used. Joules should be used instead.] |
| Micellar Paclitaxel | NCIT_C29256 | [A systemic administered polymeric micelle containing paclitaxel that may be used for chronic inflammatory diseases, such as rheumatoid arthritis and psoriasis. Paclitaxel, a toxoid, binds to and stabilizes tubulin and inhibits the disassembly of microtubules, thereby inhibiting cell division. Paclitaxel also inhibits metalloproteinase, thereby blocking the activities of matrix metalloproteinases (MMPs) and preventing collagen degradation in cartilage and bone.] |
| Thyroid Gland Anaplastic Carcinoma, Osteoclastic Variant | NCIT_C7906 | [An extremely rare morphologic variant of anaplastic carcinoma of the thyroid gland, characterized by the presence of large numbers of non-neoplastic, osteoclast-like giant cells.] |
| Undifferentiated Carcinoma with Osteoclast-Like Giant Cells | NCIT_C63622 | [A usually aggressive malignant epithelial neoplasm composed of atypical cells which do not display evidence of glandular or squamous differentiation and giant cells resembling osteoclasts.] |
| Thyroid Gland Anaplastic Carcinoma | NCIT_C3878 | [A primary carcinoma of the thyroid gland composed of undifferentiated cells. The malignant cells demonstrate evidence of epithelial differentiation, either by immunohistochemistry or electron microscopic studies. Microscopically, in the majority of cases there is a mixture of spindle, epithelioid, and giant cells. The vast majority of the patients present with a rapidly enlarging neck mass. The clinical course is usually aggressive.] |
| Femtomole | NCIT_C68854 | [A unit of amount of substance equal to one quadrillionth of a mole (10E-15 mole).] |
| Miconazole Nitrate | NCIT_C29257 | [The nitrate salt form of miconazole, an antifungal synthetic derivative of imidazole and used in the treatment of candidal skin infections, Miconazole selectively affects the integrity of fungal cell membranes, high in ergosterol content and different in composition from mammalian cells membranes. (NCI04)] |
| Thyroid Gland Undifferentiated Small Cell Carcinoma | NCIT_C7907 | |
| Attomole | NCIT_C68855 | [A unit of amount of substance equal to one quintillionth of a mole (10E-18 mole).] |
| Pyrilamine/Caffeine/Acetaminophen | NCIT_C29258 | [A combination preparation containing pyrilamine, caffeine and acetaminophen. Pyrilamine is an ethylenediamine antihistamine that blocks H1 receptors and exerts local anesthetic, sedative and mild analgesic activities. Caffeine is a central nervous system stimulant. Acetaminophen possesses analgesic and antipyretic effects. This preparation is used for the relief of premenstrual and menstrual symptoms.] |
| Recurrent Thyroid Gland Carcinoma | NCIT_C7908 | [The reemergence of a thyroid gland carcinoma after a period of remission.] |