Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Gangrenous Stomatitis	NCIT_C34852	[Gangrene of the mucous membranes of the mouth leading to ulcers and destruction of the soft tissues of the face and bones. It usually occurs in malnourished children in areas of poor sanitation and immunocompromised patients.]
Non-Autoimmune Hemolytic Anemia	NCIT_C34853	[Hemolytic anemia that is not mediated by immune mechanisms.]
Noonan Syndrome	NCIT_C34854	[A genetic syndrome caused by mutations in the PTPN11 gene (over 50% of the cases) or less frequently mutations in the SOS1, RAF1, or KRAS genes. It is characterized by short stature, webbed neck, hypertelorism, low-set ears, deafness, and thrombocytopenia or abnormal platelet function.]
Norwegian Scabies	NCIT_C34855	[A rare, severe form of scabies that is associated with immunosuppression. It is characterized by an immense number of mites and hyperkeratotic crusted lesions, and is usually accompanied by lymphadenopathy and eosinophilia.]
Scabies	NCIT_C34998	[A contagious skin infection that is caused by the burrowing parasitic mite, Sarcoptes scabiei, and is characterized by intense itching and small, raised red spots in the area of the mite burrows.]
Brain Disorder	NCIT_C96413	[A non-neoplastic or neoplastic disorder that affects the brain.]
Mental Disorder Due to a General Medical Condition	NCIT_C92199	[A category of psychiatric disorders which are the direct physiologic consequence of a general medical condition.]
Organic Affective Syndrome	NCIT_C34871	[A mental disorder caused by intrinsic disease which is characterized by persistent alterations in mood that are directly attributable to the disease itself rather than a response to knowledge of the disease or other co-morbidity. It may be broadly classified as a depressive or bipolar disorder due to a general medical condition.]
Organic Brain Syndrome	NCIT_C34868	[A mental disorder caused by intrinsic disease which is characterized by acute or chronic impairment of intellectual functioning, behavior, mood or judgment. It is attributable to a medical etiology and excludes a primary psychiatric cause. A chronic course usually correlates to a poorer prognosis.]
Organic Personality Syndrome	NCIT_C34872	[A mental disorder caused by intrinsic disease which is characterized by persistent alteration of a known behavioral pattern. Changes in emotional stability, motivation, judgment or impulse control are usually noted. It is broadly classified as a personality change due to a general medical condition.]
Ornithosis	NCIT_C34873	[Disease caused by the Chlamydophila psittaci bacteria, usually transmitted from birds to humans.]
Chlamydophila psittaci Infection	NCIT_C44959	[A bacterial infection caused by Chlamydophila psittaci. Humans are infected by handling sick birds. The Chlamydiae cause respiratory infection manifests with fever, malaise, cough, dyspnea, sore throat, photophobia and headaches.]
HeLa	NCIT_C20226	[HeLa cells were developed from cervix adenocarcinoma of a 31-year-old Black female. The cells are positive for keratin by immunoperoxidase staining. HeLa cells have been reported to contain human papilloma virus 18 (HPV-18) sequences. P53 expression was reported to be low, and normal levels of pRB (retinoblastoma suppressor) were found. Four typical HeLa marker chromosomes have been reported. M1 is a rearranged long arm and centromere of chromosome 1 and the long arm of chromosome 3. M2 is a combination of short arm of chromosome 3 and long arm of chromosome 5. M3 is an isochromosome of the short arm of chromosome 5. M4 consists of the long arm of chromosome 11 and an arm of chromosome 19. HeLa Marker Chromosomes: One copy of Ml, one copy of M2, four-five copies of M3, and two copies of M4 as revealed by G-banding patterns.]
Tumor Cell Line	NCIT_C20313
HeLa S3	NCIT_C20227	[HeLa S3 is a clonal derivative of the parent HeLa line. S3 was cloned in 1955 by T.T. Puck, P.I. Marcus, and S.J. Cieciura. This line can be adapted to grow in suspension.]
Cell Clone	NCIT_C16441	[A population of genetically identical cells derived by mitosis from a single progenitor.]
HeLa/SF	NCIT_C20228	[HeLa/SF is a derivative of HeLa adapted to grow in serum free medium. Over time, the serum component of the medium was replaced with TCH, a defined multipurpose serum replacement.]
HL-60/MX2	NCIT_C20229	[HL-60/MX2 is a mitoxantrone resistant derivative of the HL-60 cell line. HL-60/MX2 is approximately 35 fold less sensitive to mitoxantrone than the HL-60 parental cells. HL-60/MX2 cells are cross-resistant to etoposide, teniposide, bisantrene, dactinomycin, 4'-(9-acridinylamino)methane- sulfon-m-anisidide, and the anthracyclines daunorubicin and doxorubicin but retain sensitivity to the Vinca alkaloids vincristine and vinblastine, melphalan, mitomycin C and cisplatin. In addition, the HL-60/MX2 cells display slight collateral sensitivity to bleomycin. Resistance to mitoxantrone is stable for up to six months.]
Rat Cell Line	NCIT_C20222
hGH Gene	NCIT_C20223	[HGH Genes (Somatotropin/Prolactin Family) share a high degree of sequence identity and encode alternatively spliced diverse isoforms of Growth Hormone, a small secreted peptide hormone that affects gene expression, metabolism, and growth control. Due to alternative splicing, differential posttranslational modifications, optional binding to GHBP or alpha2-macroglobulin, and potential proteolytic processing, circulating GH shows great heterogeneity as a disulfide-linked or non-covalently associated monomer, dimer, trimer, tetramer, or pentamer in homopolymeric and heteropolymeric combinations. GH stimulates the liver and other tissues to secrete IGF-1. GH stimulates amino acid uptake and protein synthesis in muscle and other tissues and stimulates differentiation and proliferation of myoblasts. GH also stimulates mitosis, cell growth, and differentiation of other cell types. (NCI)]