Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
F-18 Fluoroethyltyrosine	NCIT_C60818	[An amino acid analog radiolabeled with fluorine F 18, a positron emitting isotope, used as a tracer in positron emission tomography (PET). Reflecting the increased amino acid transport capacity of tumor cells, F-18 fluroethyltyrosine (F-18 FET) is actively taken up in tumor cells via the amino acid transport system, but is neither incorporated into proteins nor readily degraded, resulting in high intracellular concentrations of this imaging agent. Radiolabeled amino acid-based agents are useful in PET brain tumor imaging because F-18 fluoro-deoxyglucose (F-18 FDG), commonly used in PET tumor imaging, is relatively insensitive for detecting tumors in the brain due to high levels of glycolytic metabolism in the normal cortex and to a lesser extent in white matter.]
Diagnostic Reagent	NCIT_C1937	[Any reagent that is used in vitro or in vivo for detection or screening of a particular disease or any health-related issue.]
Assay	NCIT_C60819	[A qualitative or quantitative analysis performed to determine the amount of a particular constituent in a sample or the biological or pharmacological properties of a drug.]
Mixed Category Laboratory Procedure	NCIT_C74957	[A laboratory procedure that is performed in more than one of these laboratory specializations: anatomic pathology, clinical pathology, or molecular pathology.]
Columnar Metaplasia	NCIT_C35846	[A morphologic finding indicating the transformation of non-columnar epithelial cells into columnar cells.]
Epithelial Metaplasia	NCIT_C96363	[A morphologic finding that refers to the replacement of a group of one type of epithelial cells (e.g., glandular epithelial cells) to another type of epithelial cells (e.g., squamous epithelial cells).]
Liver Dysplastic Foci	NCIT_C35847	[A morphologic finding indicating the presence of single or multiple foci of hepatocytes that exhibit dysplastic changes. These microscopic foci measure less than 1 mm in diameter and are usually detected in cirrhotic livers.]
Digestive System Dysplasia	NCIT_C95331	[A finding indicating the presence of morphologic features of neoplasia in the epithelium of any part of the digestive system without evidence of invasion. These features include architectural and cytological epithelial alterations.]
Large Cell Dysplasia	NCIT_C35848
Small Cell Dysplasia	NCIT_C35849
Microaneurysm	NCIT_C35842	[An aneurysm that is located within the system of small blood vessels, including capillaries, venules, and arterioles, that perfuse the body's tissues.]
Aneurysm	NCIT_C26693	[Bulging or ballooning in an area of an artery secondary to arterial wall weakening.]
Traumatic Aneurysm	NCIT_C35843	[An aneurysm caused by physical injury.]
Radiation-Induced Vascular Disease	NCIT_C35844	[A vascular disease caused by radiation.]
Radiation-Related Non-Neoplastic Disorder	NCIT_C53539	[A non-neoplastic disorder arising in an anatomic site exposed to radiation.]
Basal Cell Hyperplasia	NCIT_C35845	[A pathologic hyperplastic process characterized by the proliferation of the cells of the epithelial layer that resemble the basal cells of the lower part of the epidermis.]
Juvenile Paget Disease	NCIT_C131861	[A bone disorder caused by autosomal recessive mutation(s) of the gene TNFRSF11B, which encodes tumor necrosis factor receptor superfamily member 11B. This condition is characterized by excessive osteoclastic resorption of bone followed by deposition of weak, disorganized woven bone. Clinical characteristics include short stature, enlarged skull, bony deformities, bone pain, warm skin over the affected bone, joint stiffness, headaches, hearing loss, and elevated serum alkaline phosphatase.]
Bone Paget Disease	NCIT_C3292	[A disease of bone that initially results in the excessive resorption of bone (by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue.]
Cartilaginous Metaplasia	NCIT_C35860
Mesenchymal Metaplasia	NCIT_C54710	[A morphologic finding that refers to the transformation or replacement of a group of non-mesenchymal cells into osseous, cartilagenous, or lipomatous cells.]