Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Interferon-Induced, Double-Stranded RNA-Activated Protein Kinase	NCIT_C34095	[Interferon-induced, double-stranded RNA-activated protein kinase (551 aa, ~62 kDa) is encoded by the human EIF2AK2 gene. This protein is involved in both serine/threonine phosphorylation and the inhibition of protein synthesis.]
Serine/Threonine-Protein Phosphatase 2A 56 kDa Regulatory Subunit Delta Isoform	NCIT_C34090	[Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (602 aa, ~70 kDa) is encoded by the human PPP2R5D gene. This protein may play a role in the modulation of substrate specificity for protein phosphatase 2A.]
Serine/Threonine-Protein Phosphatase 2A 56 kDa Regulatory Subunit Epsilon Isoform	NCIT_C34091	[Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (467 aa, ~55 kDa) is encoded by the human PPP2R5E gene. This protein may be involved in the modulation of the activity of protein phosphatase 2A.]
DNMT3A wt Allele	NCIT_C73653	[Human DNMT3A wt allele is located in the vicinity of 2p23 and is approximately 110 kb in length. This allele, which encodes DNA (Cytosine-5)-Methyltransferase 3A, is involved in epigenetic modification of chromatin DNA and control of gene expression.]
DNMT3A Gene	NCIT_C73652	[This gene is involved in epigenetic modification of DNA.]
DNMT1 Gene	NCIT_C73654	[This gene is involved in epigenetic modification of DNA.]
DNMT1 wt Allele	NCIT_C73655	[Human DNMT1 wt allele is located in the vicinity of 19p13.2 and is approximately 62 kb in length. This allele, which encodes DNA (Cytosine-5)-Methyltransferase 1, is involved in epigenetic modification of chromatin DNA and control of gene expression.]
PAX2 Gene	NCIT_C73656	[This gene is involved in gene expression and cellular proliferation.]
CBX5 Gene	NCIT_C73650	[This gene is involved in epigenetic repression of chromatin.]
CBX5 wt Allele	NCIT_C73651	[Human CBX5 wt allele is located in the vicinity of 12q13.13 and is approximately 39 kb in length. This allele, which encodes Chromobox Protein Homolog 5, is involved in epigenetic repression of chromatin, control of gene expression, and association of heterochromatin with the inner nuclear membrane.]
PAX2 wt Allele	NCIT_C73657	[Human PAX2 wt allele is located in the vicinity of 10q24.31 and is approximately 84 kb in length. This allele, which encodes paired box protein Pax-2, plays a role in transcription by RNA Polymerase II and in development of the central nervous system, eyes, kidney and urogenital tract.]
KAT8 Gene	NCIT_C73658	[This gene is involved in epigenetic control of gene expression.]
KAT8 wt Allele	NCIT_C73659	[Human KAT8 wt allele is located in the vicinity of 16p11.2 and is approximately 14 kb in length. This allele, which encodes histone acetyltransferase KAT8 protein, may play a role in activation of RNA polymerase II transcription.]
KMT5B wt Allele	NCIT_C73670	[Human KMT5B is located in the vicinity of 11q13.2 and is approximately 59 kb in length. This allele, which encodes histone-lysine N-methyltransferase KMT5B protein, may play a role in transcriptional repression and epigenetic modification of chromatin.]
KMT5B Gene	NCIT_C73669	[This gene plays a role in histone methylation and heterochromatin formation.]
KMT5A Gene	NCIT_C73664	[This gene plays a role in protein methylation and epigenetic control of gene expression.]
KMT5A wt Allele	NCIT_C73665	[Human KMT5A wild-type allele is located in the vicinity of 12q24.31 and is approximately 26 kb in length. This allele, which encodes N-lysine methyltransferase KMT5A protein, is involved in protein methylation and chromatin modification.]
SETD7 Gene	NCIT_C73667	[This gene is involved in epigenetic control of gene expression.]
KAT7 Gene	NCIT_C73660	[This gene is involved in epigenetic control of gene expression.]
KAT7 wt Allele	NCIT_C73661	[Human KAT7 wt allele is located in the vicinity of 17q21.32 and is approximately 40 kb in length. This allele, which encodes histone acetyltransferase KAT7 protein, may play a role in activation and repression of RNA polymerase II transcription.]