Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
DNA Methyltransferase	NCIT_C16508	[DNA Methyltransferases are a subclass of transferase enzymes that catalyze the transfer of a methyl group from a donor compound to DNA.]
DNA (Cytosine-5)-Methyltransferase 3A	NCIT_C73691	[DNA (cytosine-5)-methyltransferase 3A protein (909 aa, ~102 kDa) is encoded by the human DNMT3A gene. This soluble, nuclear protein is involved in epigenetic modification of chromatin, catalyzing the methylation of C5 in CpG dinucleotides within DNA.]
Serine/Threonine-Protein Phosphatase 2A 65 kDa Regulatory Subunit A Beta Isoform	NCIT_C34084	[Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (601 aa, ~66 kDa) is encoded by the human PPP2R1B gene. This protein is involved in the regulation of protein phosphatase 2A activity.]
Paired Box Protein Pax-2	NCIT_C73692	[Paired box protein PAX-2 (416aa, ~45 kD) is encoded by the human PAX2 gene. This soluble, nuclear protein plays a role in transcription by RNA polymerase II and cellular proliferation.]
Serine/Threonine Protein Phosphatase 2A Catalytic Subunit Alpha Isoform	NCIT_C34080	[Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (309 aa, ~36 kDa) is encoded by the human PPP2CA gene. This protein plays a role in signaling, apoptosis and protein dephosphorylation.]
Absorbance Unit	NCIT_C73686	[A unit of optical density expressed as the absorbance of light transmitted through the medium on the logarithmic scale.]
Absorbance Unit per Minute	NCIT_C73687	[A unit of a speed of optical density change expressed as a logarithm of absorbance of light transmitted through a partially absorbing substance per minute.]
Count per Minute	NCIT_C73688	[A unit of frequency expressed as a number of events per minute.]
Chromobox Protein Homolog 1	NCIT_C73682	[Chromobox protein homolog 1 (185 aa, ~21 kDa) is encoded by the human CBX1 gene. This soluble, nuclear protein plays a role in epigenetic repression of chromatin and association of heterochromatin with the inner nuclear membrane.]
Chromobox Protein Homolog 3	NCIT_C73683	[Chromobox protein homolog 3 (183 aa, ~21 kDa) is encoded by the human CBX3 gene. This soluble, nuclear protein plays a role in epigenetic repression of chromatin and association of heterochromatin with the inner nuclear membrane.]
E3 SUMO-Protein Ligase CBX4	NCIT_C73684	[E3 SUMO-protein ligase CBX4 (558 aa, ~61 kDa) is encoded by the human CBX4 gene. This soluble, nuclear protein plays a role in repressing the expression of genes through SUMOylation of lysine 119 of histone H2A.]
Chromobox Protein Homolog 5	NCIT_C73685	[Chromobox protein homolog 5 (191 aa, ~22 kDa) is encoded by the human CBX5 gene. This soluble, nuclear protein plays a role in epigenetic modification of chromatin, by catalyzing the monomethylation of lysine 5 of histone H2B. The outcome of this modification is associated with either activated gene transcription, or, if further processed to trimethylated lysine 5, epigenetically repressed gene transcription. By affecting the balance of chromatin in heterochromatin and euchromatin at specific gene loci, this protein acts as a candidate tumor suppressor.]
PC4 and SFRS1-Interacting Protein Isoform 2	NCIT_C34096	[PC4 and SFRS1-interacting protein isoform 2 (333 aa, ~38 kDa) is encoded by the human PSIP1 gene. This protein is involved in both transcriptional regulation and mRNA splicing.]
PSIP1 Gene Product	NCIT_C147522	[A protein encoded by the PSIP1 gene.]
PC4 and SFRS1-Interacting Protein Isoform 1	NCIT_C34097	[PC4 and SFRS1-interacting protein isoform 1 (530 aa, ~60 kDa) is encoded by the human PSIP1 gene. This protein plays a role in transcriptional regulation, neurogenesis and HIV infection.]
Protein Patched Homolog 2	NCIT_C34098	[Protein patched homolog 2 (1203 aa, ~131 kDa) is encoded by the human PTCH2 gene. This protein plays a role in hedgehog signaling pathways.]
Protein-Tyrosine Kinase 6	NCIT_C34099	[Protein-tyrosine kinase 6 (451 aa, ~52 kDa) is encoded by the human PTK6 gene. This protein is involved in both signal transduction and protein phosphorylation.]
PR Domain Zinc Finger Protein 1	NCIT_C34092	[PR domain zinc finger protein 1 (825 aa, ~92 kDa) is encoded by the human PRDM1 gene. This protein is involved in the negative regulation of gene expression.]
PR Domain Zinc Finger Protein 4	NCIT_C34093	[PR domain zinc finger protein 4 (801 aa, ~88 kDa) is encoded by the human PRDM4 gene. This protein plays a role in transcriptional regulation, cell cycle progression, cell proliferation and signal transduction.]
cGMP-Dependent Protein Kinase 2	NCIT_C34094	[cGMP-dependent protein kinase 2 (762 aa, ~87 kDa) is encoded by the human PRKG2 gene. This protein is involved in cyclic GMP-dependent protein phosphorylation.]