Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Glunicate	NCIT_C87632	[A long-acting nicotinic acid derivative with antilipidemic activity. Glunicate has more prolonged activity on plasma free fatty acids and triglycerides, with longer lasting and more intense activity on plasma cholesterol than nicotinic acid or its derivative, niceritrol. In animal models glunicate showed dose-dependent protection of the arterial wall from atheromatous lesions and from cholesterol and collagen accumulation. These effects were independent of its effects on lowering plasma lipid levels.]
Niacin-based Antilipidemic Agent	NCIT_C98151	[An antilipidemic agent that works through, or mimics, the action of niacin to increase HDL-C levels by blocking hepatic uptake of apolipoprotein A-1 and decreasing HDL clearance. The use of free niacin is limited by its side effects of skin flushing (i.e., redness, itching, burning, and paresthesias).]
Moxipraquine	NCIT_C87633
Sitamaquine	NCIT_C73010
Fenpiverinium	NCIT_C87638
Flutropium	NCIT_C87639
Quinocide	NCIT_C73004
Integration	NCIT_C48038	[An operation used in calculus whereby the integral of a function is determined.]
Artesunate	NCIT_C73005	[A water-soluble, semi-synthetic derivative of the sesquiterpine lactone artemisinin with anti-malarial, anti-schistosomiasis, antiviral, and potential anti-neoplastic activities. Upon hydrolysis of artesunate's active endoperoxide bridge moiety by liberated heme in parasite-infected red blood cells, reactive oxygen species and carbon-centered radicals form, which have been shown to damage and kill parasitic organisms. Additionally, in vitro studies demonstrate that this agent induces DNA breakage in a dose-dependent manner. Artesunate has also been shown to stimulate cell differentiation, arrest the cell cycle in the G1 and G2/M phases, inhibit cell proliferation, and induce apoptosis through mitochondrial and caspase signaling pathways. Artemisinin is isolated from the plant Artemisia annua.]
Spot	NCIT_C48039	[A mark on a substance or body made by foreign matter; a blot; a place discolored.]
Tafenoquine	NCIT_C73006
Benzetimide	NCIT_C73007
Marriage	NCIT_C48033	[The social institution involving legal and/or religious sanction whereby men and women are joined together for the purpose of founding a family unit; the state of being a married couple.]
Amopyroquine	NCIT_C73000
Artemether	NCIT_C73001
Artemotil	NCIT_C73002
Operator	NCIT_C48036	[A person that operates some apparatus or machine.]
Pamaquine	NCIT_C73003
Pyridoxine Hydrochloride	NCIT_C48030	[The hydrochloride salt form of pyridoxine, a water-soluble vitamin B. Pyridoxine hydrochloride is converted into the active form, pyridoxal 5'-phosphate (PLP), an essential cofactor in many enzymatic activities including synthesis of amino acids, neurotransmitters, and sphingolipids. This vitamin is essential to red blood cell, nervous system, and immune systems functions and helps maintain normal blood glucose levels.]
Ziprasidone Hydrochloride	NCIT_C48031	[The hydrochloride salt form of ziprasidone, a benzothiazolylpiperazine derivative and an atypical antipsychotic agent with an antischizophrenic property. Ziprasidone hydrochloride functions as an antagonist at the dopamine D2 and serotonin 5-HT2A and 5-HT1D receptors, and as an agonist at the 5-HT1A receptor. Ziprasidone hydrochloride also inhibits synaptic reuptake of serotonin and norepinephrine. The mechanism of action by which ziprasidone hydrochloride exerts its antischizophrenic effect is unknown but is potentially mediated through a combination of dopamine D2 and serotonin 5-HT2 antagonism. This agent also has antagonistic activity against histamine H1 and alpha-1-adrenergic receptors.]