Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Ziprasidone Mesylate	NCIT_C48032	[The mesylate salt form of ziprasidone, a benzothiazolylpiperazine derivative and an atypical antipsychotic agent with an antischizophrenic property. Ziprasidone mesylate functions as an antagonist at the dopamine D2 and serotonin 5-HT2A and 5-HT1D receptors, and as an agonist at the 5-HT1A receptor. Ziprasidone mesylate also inhibits the synaptic reuptake of serotonin and norepinephrine. The mechanism of action by which ziprasidone mesylate exerts its antischizophrenic effect is unknown but is potentially mediated through a combination of dopamine D2 and serotonin 5-HT2 antagonism. This agent also has antagonistic activity against histamine H1 and alpha-1-adrenergic receptors.]
Hexopyrronium	NCIT_C87640
Oxomemazine	NCIT_C73008
Abunidazole	NCIT_C73009
Teneligliptin	NCIT_C87623	[A long-acting, orally bioavailable, pyrrolidine-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Teneligliptin may also reduce plasma triglyceride levels through a sustained increase in GLP-1 levels.]
Tibeglisene	NCIT_C87624	[An insulin sensitizer with hypoglycemic activity. Tibeglisene is also able to reduce serum triglyceride and cholesterol concentrations.]
Feniodium	NCIT_C87625
Pretamazium	NCIT_C87626
Melogliptin	NCIT_C87620	[A potent, selective and orally bioavailable, cyanopyrrolidine-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.]
Pemaglitazar	NCIT_C87621	[A dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist, with hypoglycemic activity.]
Glitazar Antidiabetic Agent	NCIT_C98233	[Any agent within the glitazar class that are dual or pan-acting peroxisome proliferator-activated receptor (PPAR) agonists with insulin sensitizing and lipid lowering activity. Glitarzars bind to two or more subtypes of PPAR isoforms, and result in improving hyperglycemia and lipid abnormalities as seen by decreasing levels of glucose, triglycerides and increasing levels of HDL cholesterol. These agents may be used to improve glucose tolerance without inducing adiposity and body weight gain. PPARs function as transcription factors that regulate expressions of genes involved in cellular differentiation, development, and metabolism (carbohydrate, lipid, protein), and tumorigenesis.]
Sipoglitazar	NCIT_C87622	[A dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist, with hypoglycemic activity.]
Santonin	NCIT_C87627
Mefeserpine	NCIT_C87628
Moxonidine	NCIT_C87629
Spotting	NCIT_C48060	[The act of creating a spot.]
Collision-Induced Dissociation	NCIT_C48061	[A method by which fragmentation can be achieved. CID is accomplished by selecting an ion of interest with the mass analyzer and then subjecting that ion to collisions with neutral atoms or molecules. The resulting fragment ions are then mass analyzed. (from The Expanding Role of Mass Spectrometry in Biotechnology by Gary Siuzdak)]
Encyprate	NCIT_C87612
Esreboxetine Succinate	NCIT_C87613
Fantridone Hydrochloride Anhydrous	NCIT_C87614