Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Widely Invasive Lesion	NCIT_C60987
Ring Dosage Form	NCIT_C60988	[A solid composed active and/or inert ingredient(s) of in the shape of a hoop.]
Stethescope	NCIT_C69320	[A medical instrument for listening to the sounds generated inside the body.]
ADCS-ADL Severe Dementia - Description of Optimal Performance of Walking	NCIT_C106980	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, Severe Dementia (ADCS-ADL Severe Dementia) Regarding walking (or getting around in a wheelchair) in the past 4 weeks, which best describes subject's optimal performance?]
ADCS-ADL Severe Dementia - Usual Bowel and Bladder Function at Toilet	NCIT_C106981	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, Severe Dementia (ADCS-ADL Severe Dementia) Regarding bowel and bladder function at the toilet, which best describes subject's usual performance during the past 4 weeks?]
ADCS-ADL MCI - Subscore for Items 4 to 7	NCIT_C106971	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) Subscore for page 2. (Range = 0-8).]
Drop Solution Dosage Form	NCIT_C60992	[A solution intended for administration in a drop-wise fashion.]
ADCS-ADL MCI - Subscore for Items 8 to 10	NCIT_C106972	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) Subscore for page 3. (Range = 0-10).]
Neoplastic Epithelial Small Polygonal Cell	NCIT_C60993
Neoplastic Epithelial Polygonal Cell	NCIT_C37036
ADCS-ADL MCI - Subscore for Items 11 to 12	NCIT_C106973	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) Subscore for page 4. (Range = 0-7).]
Gel Forming Drop Solution Dosage Form	NCIT_C60994	[A solution intended for administration in a drop-wise fashion; it becomes gelatinous upon administration.]
ADCS-ADL MCI - Subscore for Items 13 to 14	NCIT_C106974	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) Subscore for page 5. (Range = 0-6).]
Drop Suspension Dosage Form	NCIT_C60995	[A suspension intended for administration in a drop-wise fashion.]
Drop Dosage Form	NCIT_C29012	[A substance intended for administration in a drop-wise fashion.]
ADCS-ADL MCI - Subscore for Items 15 to 16	NCIT_C106975	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) Subscore for page 6. (Range = 0-5).]
Liver X Receptor beta Agonist RGX-104	NCIT_C131910	[An orally bioavailable agonist of the nuclear receptor liver X receptor beta (LXRbeta; NR1H2; LXR-b), with potential immunomodulating and antineoplastic activities. Upon oral administration, LXRbeta agonist RGX-104 selectively targets and binds to LXRbeta, thereby activating LXRbeta-mediated signaling, leading to the transcription of certain tumor suppressor genes and the downregulation of certain tumor promoter genes. This particularly activates the expression of apolipoprotein E (ApoE), a tumor suppressor protein, in tumor cells and certain immune cells. This activates the innate immune system, resulting in depletion of immunosuppressive myeloid-derived suppressor cells (MDSCs), tumor cells and endothelial cells in the tumor microenvironment. This reverses immune evasion, enhances anti-tumor immune responses and inhibits proliferation of tumor cells. LXRbeta, a member of the oxysterol receptor family, which is in the nuclear receptor family of transcription factors, plays a key role in cholesterol transport, glucose metabolism and the modulation of inflammatory responses; activation of LXRbeta suppresses tumor cell invasion, angiogenesis, tumor progression, and metastasis in a variety of tumor cell types. The expression of the ApoE protein becomes silenced in human cancers as they grow, become invasive, and metastasize; ApoE silencing is related to reduced survival in cancer patients. The LXR-ApoE pathway regulates the ability of cancers to evade the immune system and recruit blood vessels.]
ADCS-ADL MCI - Subscore for Item 17	NCIT_C106976	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) Subscore for page 7. (Range = 0-4).]
Burkitt-Like Lymphoma with 11q Aberration	NCIT_C131911	[A molecularly distinct B-cell lymphoma reminiscent of Burkitt lymphoma. It is characterized by the absence of MYC translocation and the presence of chromosome 11q aberrations.]
Aggressive Non-Hodgkin Lymphoma	NCIT_C9244	[A non-Hodgkin lymphoma with an aggressive clinical course. Representative examples include Burkitt lymphoma, mantle cell lymphoma, and angioimmunoblastic T-cell lymphoma.]