Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Policy Research	NCIT_C15999	[Research studies assessing the effect of policies, including worksite, community, state and Federal policies as related to a variety of health issues.]
Research Activity	NCIT_C15429	[Systematic investigation into a subject in order to discover facts, establish or revise a theory, or develop a plan of action based on the facts discovered.]
GD3 Binding	NCIT_C40955	[GD3 Binding Interaction involves non-covalent attachment of a molecule through intermolecular physical forces of attraction to a cell surface liposaccharide disialoganglioside, GD3.]
Testicular Seminoma, Cribriform Variant	NCIT_C40957	[A morphologic variant of testicular seminoma characterized by the presence of seminoma cells arranged in cribriform patterns and few lymphocytes.]
Testicular Seminoma	NCIT_C7328	[A malignant germ cell tumor arising from the testis. It is believed that it is derived from the sexually undifferentiated embryonic gonad. Treatment with radiotherapy is highly successful when the tumor is diagnosed in localized stages, which represents the majority of presentations of seminoma.]
Dedifferentiated Malignant Infiltrate	NCIT_C126770	[A morphologic finding indicating the presence of a high grade undifferentiated malignant cellular infiltrate and a second component of a low grade malignant cellular infiltrate in a tissue sample.]
Testicular Seminoma, Pseudoglandular Variant	NCIT_C40958	[A morphologic variant of testicular seminoma characterized by the presence of seminoma cells arranged in pseudoglandular patterns and few lymphocytes.]
DUSP4 Gene	NCIT_C112127	[This gene is involved in the dephosphorylation of MAPK1 and MAPK3.]
Protein Phosphatase Gene	NCIT_C20731	[Protein Phosphatase Genes encode Protein Phosphatases, enzymes that remove tyrosine-, serine-, or threonine-bound phosphate groups from many phosphoproteins, including many enzymes phosphorylated by a tyrosine kinase or a serine/threonine kinase. (NCI)]
Testicular Seminoma, Tubular Variant	NCIT_C40959	[A morphologic variant of testicular seminoma characterized by the presence of seminoma cells arranged in tubular patterns and few lymphocytes.]
DUSP4 wt Allele	NCIT_C112128	[Human DUSP4 wild-type allele is located within 8p12-p11 and is approximately 18 kb in length. This allele, which encodes dual specificity protein phosphatase 4 protein, plays a role in the dephosphorylation of MAP kinases.]
MAPK Signaling Pathway	NCIT_C38834
8p12-p11.2	NCIT_C13774	[A chromosome band present on 8p]
Dual Specificity Protein Phosphatase 4	NCIT_C112129	[Dual specificity protein phosphatase 4 (394 aa, ~43 kDa) is encoded by the human DUSP4 gene. This protein is involved in the dephosphorylation of mitogen-activated protein kinase-1 and -3.]
Dual-Specificity Phosphoprotein Phosphatase	NCIT_C25880	[Dual-specificity protein phosphatases are a subclass of protein tyrosine phosphatases that are uniquely able to hydrolyse the phosphate ester bond on both a tyrosine and a threonine or serine residue on the same protein. Dual-specificity phosphatases have a central role in the complex regulation of signalling pathways that are involved in cell stress responses, proliferation and death. (from Nat Rev Drug Discov 2002;1:961-76)]
LGALS9 Gene	NCIT_C112123	[This gene plays a role in carbohydrate binding.]
Pseudoporphyria	NCIT_C112124	[A drug-induced photodermatosis characterized by skin fragility, erythema, and the appearance of tense bullae, erosions and scarring in the absence of abnormalities in porphyrin metabolism.]
Dermatosis	NCIT_C27554	[A disorder involving lesions or eruptions of the skin, usually without inflammation.]
LGALS9 wt Allele	NCIT_C112125	[Human LGALS9 wild-type allele is located in the vicinity of 17q11.2 and is approximately 20 kb in length. This allele, which encodes galectin-9 protein, is involved in carbohydrate binding and may be an eosinophil chemoattractant. Overexpression of the gene may be associated with Hodgkin lymphoma.]
17q11.2	NCIT_C13619	[A chromosome band present on 17q]