Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Galectin-9	NCIT_C112126	[Galectin-9 (355 aa, ~40 kDa) is encoded by the human LGALS9 gene. This protein plays a role in galactoside binding and as an eosinophil chemoattractant.]
Peripheral Blood Lymphocyte	NCIT_C12938
Lectin	NCIT_C16785	[Proteins that specifically bind to the branching sugar molecules of glycoproteins and glycolipids on cell surfaces to cause biochemical changes. They are often classified according to either the saccharide or sugar specificity.]
PDIA3 wt Allele	NCIT_C112120	[Human PDIA3 wild-type allele is located in the vicinity of 15q15 and is approximately 27 kb in length. This allele, which encodes protein disulfide-isomerase A3 protein, plays a role in both the rearrangement of protein disulfide bonds and antigen presentation.]
PDIA3 Gene	NCIT_C112118	[This gene is involved in both antigen presentation and formation of disulfide bonds in proteins.]
Antigen Processing and Presentation Pathway	NCIT_C91433
15q15	NCIT_C28662	[A chromosome band present on 15q]
Chaperone Protein Interaction Process	NCIT_C40952	[Chaperone Protein Interaction involves temporary non-covalent binding through intermolecular physical forces of attraction by cellular proteins that mediate assembly/disassembly, stabilization, and transmembrane translocation of other polypeptides or complexes, but which are not components of those final structures.]
Molecular Interaction Process	NCIT_C18219	[Involves temporary, non-covalent binding of two or more molecules as a result of intermolecular physical forces and often involves spatial complementarity between the interacting objects.]
Protein Disulfide-Isomerase A3	NCIT_C112121	[Protein disulfide-isomerase A3 (505 aa, ~57 kDa) is encoded by the human PDIA3 gene. This protein is involved in both the activity of the MHC class I peptide-loading complex and post-translational disulfide bond formation.]
Isomerase	NCIT_C16759	[An enzyme that transfers functional groups to catalyze the geometric or structural rearrangement of atoms within a given molecule to form an isomer of the original molecule.]
Free Radical Binding	NCIT_C40953	[Free Radical Binding involves temporary interaction with chemically unstable and highly reactive molecules (free radicals) having an unsatisfied electron valence pair. Agents of tissue damage through exposure to radiation, environment chemicals, and aging, reactive free radicals stabilize themselves by appropriating an electron from a nearby molecule and damaging that molecule by altering the electron number in its outermost electron shell.]
Acute Generalized Exanthematous Pustulosis	NCIT_C112122	[A widespread acute rash characterized by fever and multiple small pustules on a reddish background.]
Roundabout Homolog 3	NCIT_C126779	[Roundabout homolog 3 (1386 aa, ~148 kDa) is encoded by the human ROBO3 gene. This protein is involved in the modulation of neurite outgrowth and axon guidance.]
ROBO2 wt Allele	NCIT_C126775	[Human ROBO2 wild-type allele is located in the vicinity of 3p12.3 and is approximately 1743 kb in length. This allele, which encodes roundabout homolog 2 protein, is involved in axon guidance, cell migration and ligand binding. Chromosomal anomalies, including t(Y;3)(p11;p12), that cause dominant-negative mutations in this gene are associated with vesicoureteral reflux.]
ROBO2 Gene	NCIT_C126774	[This gene plays a role in ligand binding, axon guidance and cell migration.]
Axon Guidance Pathway	NCIT_C91455
Roundabout Homolog 2	NCIT_C126776	[Roundabout homolog 2 (1378 aa, ~151 kDa) is encoded by the human ROBO2 gene. This protein plays a role in cell migration, axon guidance and ligand binding.]
ROBO3 Gene	NCIT_C126777	[This gene is involved in neuronal cell shape.]
Cellular Migration Process	NCIT_C26169	[Cell Migration consists of active directed translocation of a whole cell, or cell body, from one site to another in response to a gradient; distinct from cell motion that involves movement of cell processes (e.g., axons, microvilli, etc.). (NCI)]