Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
ROBO3 wt Allele	NCIT_C126778	[Human ROBO3 wild-type allele is located in the vicinity of 11q24.2 and is approximately 16 kb in length. This allele, which encodes roundabout homolog 3 protein, plays a role in axon guidance and neurite outgrowth. Mutation of the gene is associated with horizontal gaze palsy with progressive scoliosis.]
Uterine Corpus Neuroendocrine Neoplasm	NCIT_C126771	[An epithelial neoplasm with neuroendocrine differentiation that arises from the uterine corpus. It includes carcinoid tumor, small cell carcinoma pulmonary type, and large cell neuroendocrine carcinoma.]
Neuroendocrine Neoplasm	NCIT_C3809	[A benign or malignant neoplasm composed of cells of neuroendocrine origin. Representative examples include paraganglioma, carcinoid tumor, and neuroendocrine carcinoma.]
Uterine Corpus Neoplasm	NCIT_C6300	[A benign or malignant neoplasm that affects the uterine corpus. Representative examples of benign neoplasms include leiomyoma, adenomyoma, endometrial stromal nodule, and endometrial polyp. Representative examples of malignant neoplasms include endometrial carcinoma, adenosarcoma, carcinosarcoma, and leiomyosarcoma.]
Endometrial Large Cell Neuroendocrine Carcinoma	NCIT_C126772	[A high grade neuroendocrine neoplasm that arises from the endometrium. It is composed of large polygonal cells arranged in well-demarcated nests, trabeculae or cords with peripheral palisading.]
Endometrial Carcinoma	NCIT_C7558	[A malignant tumor arising from the epithelium that lines the cavity of the uterine body. The vast majority of endometrial carcinomas are adenocarcinomas; squamous cell and adenosquamous carcinomas represent a minority of the cases. Endometrioid adenocarcinoma is the most frequently seen variant of endometrial adenocarcinoma. Uterine bleeding is an initial clinical sign. The prognosis depends on the stage of the tumor, the depth of myometrial wall invasion, and the degree of differentiation.]
Large Cell Neuroendocrine Carcinoma	NCIT_C6875	[A usually aggressive carcinoma composed of large malignant cells which display neuroendocrine characteristics. It is characterized by the presence of high mitotic activity and necrotic changes. The vast majority of cases are positive for neuron-specific enolase. Representative examples include lung, breast, cervical, and thymic neuroendocrine carcinomas.]
Uterine Corpus Carcinoid Tumor	NCIT_C126773	[A very rare and well differentiated neuroendocrine tumor that arises from the uterine corpus.]
Carcinoid Tumor	NCIT_C2915	[A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement.]
Bronchodilation	NCIT_C40943	[Bronchodilation involves widening of air passage lumina, typically due to bronchial smooth muscle relaxation, and leads to increased air flow.]
Respiratory Process	NCIT_C41477	[A Respiratory Process involves the function of components of the respiratory tract involved in breathing, which include the nose, throat, larynx, trachea, bronchi, and lungs.]
Respiratory Secretion Alteration	NCIT_C40944	[Respiratory Secretion Alteration involves a change in the quality of the existing state of fluid release from cells in the respiratory tract. Such alterations increase or decrease the surfactant, protective, and lubricating effects of respiratory secretions.]
Respiratory Secretion Viscosity Alteration	NCIT_C40945	[Respiratory Secretion Viscosity Alteration involves a change in the quality of the existing state of thickness of fluids released from cells in the respiratory tract. Such alterations increase or decrease blockage of air passages.]
Endometrial Metaplasia	NCIT_C126780	[A morphologic finding indicating the alteration of the mature endometrial glandular epithelium to another that differs from that of normal endometrioid glands.]
Skin-Associated Alteration	NCIT_C40946	[Skin-Associated Alteration involves a qualitative change in the existing state of activities of skin-related glands, tissues, and cells, resulting in increased or decreased integrity, functionality, or activity of skin-related structures, such as sebaceous glands.]
Endometrial Lymphoma-Like Lesion	NCIT_C126781	[Dense diffuse and superficial infiltration of the endometrium by lymphoid cells. It is typically seen in association with chronic endometritis.]
Sebaceous Gland Alteration	NCIT_C40947	[Sebaceous Gland Alteration involves a change in the existing function of cellular, cell, or tissue components of the holocrine glands of the skin situated in the corium and that secrete sebum.]
Eosinophilic Fasciitis	NCIT_C112116	[Inflammation and induration of the fascia related to an accumulation of white blood cells, including eosinophils.]
Fasciitis	NCIT_C50559	[Inflammation process in fascia.]
Vascular Malformation	NCIT_C112117	[A congenital abnormality of the arteries and veins, lymph vessels or veins and lymph vessels.]