Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Radiation Therapy	NCIT_C15313	[Treatment of a disease by means of exposure of the target or the whole body to radiation. Radiation therapy is often used as part of curative therapy and occasionally as a component of palliative treatment for cancer. Other uses include total body irradiation prior to transplantation.]
9-cis-Retinoic Acid/Interferon Alfa	NCIT_C15624	[A combination drug therapy.]
Alitretinoin	NCIT_C1574	[An orally- and topically-active naturally-occurring retinoic acid with antineoplastic, chemopreventive, teratogenic, and embryotoxic activities. Alitretinoin binds to and activates nuclear retinoic acid receptors (RAR) and retinoid X receptors (RXR); these activated receptors act as transcription factors, regulating gene expression that results in the inhibition of cell proliferation, induction of cell differentiation, and apoptosis of both normal cells and tumor cells.]
QS21/Tyrosinase Peptide	NCIT_C15625
Tyrosinase Peptide	NCIT_C2401	[One of a number of recombinant peptides consisting of amino acid residues of the enzyme tyrosinase, a protein frequently expressed by melanoma cells. Vaccination with tyrosinase peptide may stimulate cytotoxic T lymphocyte response against tyrosinase-expressing tumor cells, resulting in decreased tumor growth. (NCI04)]
QS21	NCIT_C1478	[A purified, natural saponin isolated from the soapbark tree Quillaja saponaria Molina with potential immunoadjuvant activity. When co-administered with vaccine peptides, QS21 may increase total antitumoral vaccine-specific antibody responses and cytotoxic T-cell responses.]
Neuroendocrine Therapy	NCIT_C15626
Interferon Alfa/Monoclonal Antibody CC49/Paclitaxel	NCIT_C15627
Paclitaxel	NCIT_C1411	[A compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). (NCI04)]
Interferon Alfa/Monoclonal Antibody CC49/Pentetic Acid	NCIT_C15628
Pentetic Acid	NCIT_C460	[An edetate and a chelating agent used in preparing radiopharmaceuticals. Pentetic acid (DTPA) has strong affinity for iron but also shows affinities for other heavy metals, thereby is used in the treatment of iron-storage disease and poisoning from heavy and radioactive metals. DTPA may chelate metallic moieties of unbound, extracellular radioimmunotherapeutics, thereby aggregating radioimmunotherapeutics locally to higher concentrations, and improving tumor cell radiocytotoxicity, while sparing normal tissues from the radiocytotoxic effects. In addition, DTPA is used in radioimaing procedures when complexes with radioisotopes, ex., Tc 99m or In 111.]
Keyhole Limpet Hemocyanin/MUC-1 Antigen	NCIT_C15629
Keyhole Limpet Hemocyanin	NCIT_C1139	[A natural protein isolated from the marine mollusc keyhole limpet. Keyhole limpet hemocyanin is an immunogenic carrier protein that, in vivo, increases antigenic immune responses to haptens and other weak antigens such as idiotype proteins. (NCI04)]
MUC-1 Antigen	NCIT_C2407	[MUC-1 antigen is a mammary-type apomucin, a high molecular weight transmembrane glycoprotein, of which the extracellular domain is formed by a repeating 20 amino acid sequence (in tandem) with a high content of serine and threonine on which are O-linked carbohydrate chains. MUC-1 synthesis and secretion are features of glandular epithelial tissues; MUC-1 is overexpressed in lactating breast and in breast, ovary, lung, and prostate malignancies.]
Vegan Diet	NCIT_C15630	[A type of vegetarian diet that excludes all animal products, including dairy, eggs, meat, poultry, fish, and animal fats.]
Diet	NCIT_C15222	[The customary allowance of food and drink taken by a person or an animal from day to day, particularly one especially planned to meet specific requirements of the individual, including or excluding certain items of food; a prescribed course of eating and drinking in which the amount and kind of food, as well as the times at which it is to be taken, are regulated for therapeutic purposes or selected with reference to a particular state of health.]
Aspiration	NCIT_C15631	[Procedure using suction, usually with a thin needle and syringe, to remove bodily fluid or tissue.]
70-kD Heat-Shock Protein/MUC-1 Antigen	NCIT_C15634	[A fusion protein of the MUC-1 colorectal cancer surface marker with HSP70 as a carrier. In trials as a cancer vaccine.]
Recombinant 70-kD Heat-Shock Protein	NCIT_C28696	[A recombinant peptide that is chemically identical to or similar to the endogenous 70-kD heat shock protein (HSP70). HSP70 is a molecular chaperone that prevents physiologic stress-induced cell death by inhibiting both caspase-dependent and caspase-independent apoptosis. Because this peptide is often overexpressed in tumor cells, autologous vaccination with HSP70 derived from tumor cells may stimulate the host immune system to mount a tumoricidal cytotoxic T lymphocyte (CTL) response. (NCI04)]
Carcinoma of the Eyelid Clinical Regional Lymph Nodes TNM Finding v7	NCIT_C88576	[A clinical finding about one or more characteristics of carcinoma of the eyelid, following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.]