Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Diagnostics, Cancer	NCIT_C15799	[Reagents and techniques used for the diagnosis of cancer.]
Diagnostic Reagents and Test Kits	NCIT_C15314	[3C; Product Evaluation, Research, and Monitoring; Diagnostic Reagents and Test Kits (FMB)]
Lost Medical Device	NCIT_C112329	[A finding referring to a medical device that is no longer held or possessed; incapable of being recovered or regained.]
Metastasis Induction	NCIT_C40757	[Metastasis Induction involves initiation of the spread or migration of cancer cells from one part of the body (the organ in which it first appeared) to another. The secondary tumor contains cells that are like those in the original (primary) tumor. (NCI)]
Intermediate Density Lipoprotein Cholesterol Measurement	NCIT_C112325	[The determination of the amount of intermediate density lipoprotein present in a sample.]
Cholesterol Measurement	NCIT_C105586	[The determination of the amount of total cholesterol present in a sample.]
JC Virus Antibody Measurement	NCIT_C112326	[The determination of the amount of JC Virus antibody present in a sample.]
L2-L3 Intervertebral Space	NCIT_C112327	[The space between the L2 and L3 vertebrae.]
Lumbar Region	NCIT_C34004	[The area of the body below the ribs and above the hipbones.]
L3-L4 Intervertebral Space	NCIT_C112328	[The space between the L3 and L4 vertebrae.]
Inspiratory Capacity Reversibility	NCIT_C112321	[The change in IC following administration of a bronchodilator relative to the pre-treatment IC value. (CDISC)]
Bushen-Jianpi Decoction	NCIT_C151930	[A traditional Chinese medicine (TCM) that is used for Yin deficiency of the liver, kidney and spleen, with potential immunomodulating and antineoplastic activities. Bushen-Jianpi decoction (BSJPD; BJD) consists of various herbs, including, but not limited to, Radix Codonopsis (Dang Shen), Fructus Lycii (the fruit of Chinese wolfberry), Rhizoma Atractylodis Macrocephalae (Baishu; Bai Zhu), Fructus Ligustri Lucidi, Cuscuta chinensis (Chinese dodder) seed, and Psoralea corylifolia Linn. As a TCM, Bushen-Jianpi is used as an antineoplastic agent as it is thought to invigorate the spleen and tonify the kidney, which presumably prevents or treats a variety of cancers. Upon administration of Bushen-Jianpi decoction, the ingredients in the decoction may affect signaling pathways involved in carcinogenesis and enhance the immune system by increasing the levels of numerous cytokines and a variety of immune cells, such as cytotoxic T-lymphocytes (CTLs), natural killer cells (NKs) and macrophages. It may also reduce the expression of various proteins involved in tumorigenesis.]
Traditional Chinese Medicine Formulation	NCIT_C129986	[Any pharmaceutical formulation that contains agents used in traditional Chinese medicine (TCM).]
Insulin-Like Growth Factor Binding Protein 3 Measurement	NCIT_C112322	[The determination of the amount of insulin-like growth factor binding protein 3 present in a sample.]
Anti-PRL-3 Monoclonal Antibody PRL3-zumab	NCIT_C151931	[A humanized monoclonal antibody against phosphatase of regenerating liver 3 (PRL-3; PTP4A3), with potential immunomodulating and antineoplastic activities. Upon administration, anti-PRL-3 monoclonal antibody PRL3-zumab targets, binds to and blocks PRL-3 expressed on tumor cells. Although the exact mechanism of action through which this antibody kills tumor cells has yet to be fully elucidated, PRL3-zumab binds to PRL-3. This prevents PRL-3-mediated signaling in, inhibits the proliferation of and induces apoptosis in PRL-3-expressing tumor cells. PRL-3, a member of the PRL family of protein tyrosine kinases, is upregulated in a variety of tumor cells. Its expression is associated with increased invasiveness, higher metastatic potential, increased tumor cell survival and poor prognosis.]
Interleukin 1 Beta Measurement	NCIT_C112323	[The determination of the amount of interleukin 1 beta present in a sample.]
Chemotaxis Induction	NCIT_C40751	[Chemotaxis Induction involves initiation of characteristic movement or orientation of an organism or cell along a chemical concentration gradient either toward or away from a chemical stimulus.]
STAT3 Inhibitor TTI-101	NCIT_C151932	[An orally bioavailable, binaphthol-sulfonamide-based inhibitor of signal transducer and activator of transcription 3 (STAT3), with potential antineoplastic activity. Upon oral administration, the STAT3 inhibitor TTI-101 specifically targets and binds to the phosphotyrosyl peptide binding site within the Src homology 2 (SH2) domain of STAT3. This inhibits the Janus kinase (JAK)-mediated tyrosine phosphorylation and activation of STAT3. This impedes nuclear translocation of STAT3, prevents STAT3 binding to responsive gene promoters and blocks STAT3-mediated regulation of gene expression. STAT3 regulates the transcription of genes involved in several cellular functions. STAT3 is constitutively activated in a variety of human cancers and plays a key role in neoplastic transformation, uncontrolled tumor cell proliferation, resistance to apoptosis, metastasis, immune evasion, tumor angiogenesis, epithelial-mesenchymal transition (EMT) and the Warburg effect.]
Interleukin 1 Receptor Antagonist Measurement	NCIT_C112324	[The determination of the amount of interleukin 1 receptor antagonist present in a sample.]
Leukocyte Trafficking Induction	NCIT_C40754	[Leukocyte Trafficking Induction involves initiation of circulation of white blood cells from the blood stream to tissues or secondary lymphoid organs, to the lymphatics, and back to the bloodstream via the thoracic duct.]