Terminology Service for NFDI4Health
All terms in NCIT
| Label | Id | Description |
|---|---|---|
| 1,3-Butadiene | NCIT_C29790 | [A synthetic, colorless gas that is practically insoluble in water and soluble in ethanol, ether, acetone and benzene. It is used primarily as a monomer to manufacture many different types of polymers and copolymers and as a chemical intermediate in the production of industrial chemicals. When heated, 1,3-butadiene emits acrid fumes and is flammable. In the presence of air, it oxidizes to form explosive peroxides. The primary route of potential human exposure to this compound is inhalation. Acute exposure to 1,3-butadiene can cause irritation of the eyes, nasal passages and throat. At very high concentrations, inhalation of this gas can result in headache, fatigue, decreased blood pressure and pulse rate, central nervous system damage and unconsciousness. It is known to be a human carcinogen. (NCI05)] |
| Carcinogenic Hydrocarbon | NCIT_C44351 | [An organic compound that is likely to cause cancer and contains only carbon and hydrogen that can be arranged in rows, rings, or both, and connected by single, double or triple bonds. Carcinogenic hydrocarbons are often found in petroleum, natural gas and coal and are capable of causing cancer. (NCI05)] |
| 2-Acetylaminofluorene | NCIT_C29791 | [A synthetic, light tan crystalline solid that is insoluble in water and soluble in alcohols, glycols, ether, acetic acid, and fat solvents. It is used as a positive control by toxicologists to study the carcinogenicity and mutagenicity of aromatic amines. When heated to decomposition, 2-acetylaminofluorene emits toxic fumes of nitrogen oxides. The primary routes of potential human exposure to 2-acetylaminofluorene are inhalation and dermal contact. It is reasonably anticipated to be a human carcinogen. (NCI05)] |
| 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine | NCIT_C29792 | [A synthetic, gray-white crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). It is one of the most abundant heterocyclic amines in a typical Western diet. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05)] |
| Heterocyclic Amine Carcinogen | NCIT_C45180 | [A cyclic compound that has at least one nitrogen incorporated into its structure instead of carbon and contains an amino (-NH2) group. Heterocyclic Amines are formed from cooking meat such as beef, pork, fowl, and fish when amino acids and creatine (found in muscle) react at high temperatures. Because of the high temperatures used, frying, broiling, and barbecuing produce the largest amounts of heterocyclic amines. These compounds that result from cooking meat may increase human cancer risk. (NCI05)] |
| 2-Amino-3,4-Dimethylimidazole[4,5-f]quinoline | NCIT_C29793 | [A synthetic, yellow-green crystalline solid that is soluble in dimethylsulfoxide and methanol. It is produced in small quantities for research purposes. 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline is formed naturally during the cooking of muscle-derived foods (meat and fish). Levels of this chemical produced in this manner are dependent on cooking temperature, cooking time and method of cooking (direct or indirect). 2-Amino-3-methylimidazo[4,5-f]quinoline has also been detected in processed food flavorings, beer, wine, and cigarette smoke. It is reasonably anticipated to be a human carcinogen. (NCI05)] |
| 2-Fluoroadenine | NCIT_C29794 | [A fluorinated heterocyclic 2-ring compound. 2-fluoroadenine is the base moiety for many carbocyclic and acyclic nucleoside analogues, which may be used in antineoplastic studies.] |
| Organo-halide Carcinogen | NCIT_C45183 | [A compound with carcinogenic activity that has a carbon-based backbone that may be a cyclic or non-cyclic structure with single, double or triple bonds and can have other elements besides hydrogen incorporated in its structure but has at least one halogen (chloride, bromide, fluoride, iodide, and astatine) atom substituted for one of the hydrogen atoms. (NCI05)] |
| 20-Methylcholanthrene | NCIT_C29795 | [A polycyclic aromatic hydrocarbon that consists of five fused rings with carcinogenic activity. 20-Methylcholanthrene is often used in experimental cancer studies.] |
| 2,6-Diaminopurine | NCIT_C29796 | [One of a number of organic compounds that share a similar purine structure and possess antiviral and antitumor properties. 2,6-Diaminopurine nucleosides are versatile synthetic precursors for specific N-6 modifications of antiviral and antitumor agents. (NCI04)] |
| Purine | NCIT_C786 | |
| 3-Aminobenzo[a]pyrene | NCIT_C29797 | [A polycyclic aromatic hydrocarbon belongs to the family of mutagen benzo(a)pyrene. 3-aminobenzo(a)pyrene consists of five fused rings with an amino-group attached to the third carbon atom of the aromatic hydrocarbon ring with potential carcinogenicity.] |
| 3-Nitrobenzo[a]pyrene | NCIT_C29798 | [A polycyclic aromatic hydrocarbon belongs to the family of mutagen benzo(a)pyrene. 3-nitrobenzo(a)pyrene consists of five fused rings with a nitro-group attached to the third carbon atom of the aromatic hydrocarbon ring in with potential carcinogenicity.] |
| 3-Nitrobenzo[a]pyrene trans-7,8-Dihydrodiol | NCIT_C29799 | |
| Empiric | NCIT_C54726 | [Derived from experiment and observation rather than theory.] |
| Sarcomatous Component Present | NCIT_C54727 | [A histopathologic finding characterized by the presence of malignant cells of connective tissue origin in a tumor sample. Examples of connective tissue cells that can undergo malignant transformation include smooth and skeletal muscle cells, adipose tissue cells, osteocytes, and chondrocytes.] |
| Intracanalicular Growth Pattern | NCIT_C54728 | |
| Indwelling Catheter | NCIT_C54729 | [A hollow tube left implanted in a body canal or organ, especially the bladder, to promote drainage.] |
| Catheter Device | NCIT_C50344 | [A flexible tube designed to transfer fluids into or out of the body.] |
| Common Mouse Strains | NCIT_C15150 |