Terminology Service for NFDI4Health
All terms in NCIT
| Label | Id | Description |
|---|---|---|
| 129 Mouse | NCIT_C15151 | [Inbr and colour depends on substrain (see below). Origin: Dunn 1928 from crosses of coat colour stocks from English fanciers and a chinchilla stock from Castle. This strain has a common origin with strain 101. Most substrains carry the white-bellied agouti gene AW though only a subset have the agouti pattern as many carry albino or chinchilla and/or the pink-eyed dilution gene, p, which is derived from Asian mice of the Mus musculus type (see also strains SJL, P/J and FS/Ei). (Jackson Labs/Festing)] |
| Inbred Mouse Strains | NCIT_C14421 | [Any strain of mouse that is the product of a mating between close relatives. In biological research, inbreeding allows for the selection of specific genotypes or phenotypes that are of particular importance to the study being carried out.] |
| CD-1 Nude Mouse | NCIT_C15152 | [An inbred strain of athymic, nude mouse developed by transferring the Foxn1nu gene to a CD1 mouse.] |
| Nude Mouse | NCIT_C14239 | [A hairless mutant mouse with thymic hypoplasia, lacking T-cells. They are unable to reject transplants.] |
| BALB/c Nude Mouse | NCIT_C15153 | |
| NIH-III Mouse | NCIT_C15154 | |
| Immunodeficient Mouse | NCIT_C15156 | [Any mouse strain with a faulty immune system such that its ability to fight infectious disease is compromised or ablated. Immunodeficient mice may be derived by inbreeding or genetic engineering. Immunodeficiency may also be induced by some chemicals, heavy metals, alkylating agents, radiation, and thymectomy.] |
| NU/NU Mouse | NCIT_C15155 | |
| Critical Assessment of Microarray Data Analysis | NCIT_C54720 | [A group founded to provide a forum to critically assess different techniques used in microarray data mining. It aims to establish the state-of-the-art in microarray data mining, as well as identify progress and highlight the direction for future effort. To achieve these goals, CAMDA adopted the approach of community-wide experiment, letting the scientific community analyze the same standard data sets. Researchers worldwide are invited to take the CAMDA challenge. Results of analyses are discussed and compared at an annual CAMDA conference.] |
| Mouse Strains | NCIT_C14420 | [Breeds of mice utilized for biological research.] |
| Phase 0 Trial | NCIT_C54721 | [A clinical trial that uses an investigational agent that is available only in very limited quantities and which has never previously given to humans or for which there is extremely limited human experience. Phase 0 clinical trials are intended to enable researchers to understand the path of the drug in the body and its efficacy. Adverse event reporting in Phase 0 trials is expedited.] |
| Rag1 Mouse | NCIT_C15157 | |
| Low | NCIT_C54722 | [A minimum level or position or degree; less than normal in degree, intensity or amount.] |
| Fox Chase SCID Mouse | NCIT_C15158 | [Discovered by Bosma (1980) at Fox Chase Cancer Center, the CB17 SCID mouse has an autosomal recessive mutation in the Prkdc gene which causes a severe combined immunodeficiency affecting B and T lymphocytes.] |
| SCID Mouse | NCIT_C14294 | [Severe combined immunodeficient (SCID) mice like their human counterparts with immunodeficiency diseases are helpless not only to fight infection but also to reject transplanted tissue. These animals lack both T and B-cells and are used extensively in researches of immune disease or tissue transplantation.] |
| Intracytoplasmic and Extracytoplasmic Eosinophilic Material Present | NCIT_C54723 | |
| SCID Beige Mouse | NCIT_C15159 | |
| Adenocarcinoma Cell with Abundant Pale Cytoplasm | NCIT_C54724 | |
| Neoplastic Large Cell with Abundant Pale Cytoplasm | NCIT_C37163 | |
| Fibrotic Stroma with Finger-Like Projections Present | NCIT_C54725 |