Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
SHBG Gene	NCIT_C21169	[This gene is involved in the regulation of steroid hormones.]
Transport Protein Gene	NCIT_C28533	[Transport Protein Genes encode a diverse group of proteins that function as carriers of ligands through solubility barriers such as aqueous body fluids or in active transport across cell membranes. (NCI)]
Lipid Binding	NCIT_C20738	[Lipid Binding is the molecular interaction between a lipid molecule and a macromolecule (usually protein) for transport, catalysis, localization, or modification of function.]
Lipid Transport	NCIT_C20739	[Any subcellular or molecular event, process, or condition involved in translocation of a lipid macromolecule from one site or compartment to another. (NCI)]
Clinical Trial Agreement	NCIT_C60777	[A legally binding document which governs the administrative/legal terms under which a Study will be conducted. This includes rights regarding publication, confidential information, ownership, use of data, intellectual property, and indemnification. The Final Budget, which must be reviewed and approved by the Institution, and the Protocol are incorporated into the Clinical Trial Agreement.]
Performance	NCIT_C60778	[An action that is carried out or accomplished.]
Pazopanib Hydrochloride	NCIT_C60779	[The hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated.]
c-KIT Inhibitor	NCIT_C159198	[Any agent that inhibits the receptor tyrosine kinase mast/stem cell factor receptor c-Kit (SCFR; cKIT; CD117).]
PDGFR Inhibitor	NCIT_C159199	[Any agent that inhibits the platelet-derived growth factor receptor (PDGFR).]
VEGFR Tyrosine Kinase Inhibitor	NCIT_C93259	[Any substance that inhibits vascular endothelial growth factor receptor, a family of tyrosine kinase receptors involved in the formation of blood vessels.]
FGFR Inhibitor	NCIT_C155727	[Any agent that inhibits the fibroblast growth factor receptor (FGFR).]
Growth Arrest Specific Protein	NCIT_C21175
Protein or Riboprotein Complex	NCIT_C21176	[Multimeric subcellular structures containing proteins, and possibly, RNA.]
Gene Product	NCIT_C26548	[A protein, RNA or a complex that contains proteins and/or RNA.]
Liter per Day	NCIT_C69110	[A metric unit of volumetric flow rate defined as the rate at which one liter of matter crosses a given surface during the period of time equal to one day.]
MRE11/RAD50 Double-Strand Break Repair Complex	NCIT_C21177	[The MRE11/RAD50 double-strand break repair complex consists of 5 proteins: Nibrin, p200, p400, MRE11, and RAD50. This complex possesses manganese-dependent single-stranded DNA endonuclease and 3-prime to 5-prime exonuclease activities. In mammalian cells, this complex is important for double-strand break repair, meiotic recombination, and telomere maintenance. It functions in diverse aspects of the cellular response to double strand breaks (DSBs), including the detection of DNA damage, the activation of cell cycle checkpoints, and DSB repair. (from OMIM)]
Repair Complex	NCIT_C13723	[Initial or intermediate protein-DNA complexes present during the process of DNA repair.]
Cartridge Needle	NCIT_C69111
NBN Gene	NCIT_C21178	[This gene plays a role in DNA repair and cell cycle checkpoints.]
Homologous Recombination Repair Gene	NCIT_C153246	[A gene involved in homologous recombination repair of DNA double-strand breaks.]