Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Carcinogenic Polycyclic Aromatic Hydrocarbon	NCIT_C45188	[Carcinogenic Polycyclic Aromatic Hydrocarbons (PAH) are ubiquitous environmental pollutants that are formed in the process of incomplete burning of organic material and can cause cancer in humans. PAH molecules are made up of two or more fused aromatic rings. PAH causes a carcinogenic effect by metabolic activation to diol epoxides, which bind covalently to DNA. (NCI05)]
Tobacco-Associated Carcinogen	NCIT_C1956	[A chemical that is present in tobacco products, including pipe, cigarette and cigar as well as chewing tobacco and snuff, or that is produced during the burning of tobacco and causes a carcinogenic effect in humans.]
4-Methylnitrosamino-1,3-pyridyl-1-butanone	NCIT_C29801	[A yellowish crystalline solid nitrosamine that naturally occurs in tobacco products by oxidation and nitrosation of nicotine during the making and smoking of tobacco. 4-Methylnitrosamino-1,3-pyridyl-1-butanone is only used as a research chemical to induce tumorigenesis. This substance is reasonably anticipated to be a human carcinogen. (NCI05)]
Carcinogenic Nitrosamine	NCIT_C45398	[An organic N-nitroso compound with possible carcinogenic activity characterized by the group -NNO or -NHNO in its structure, formed by combining nitrates with amines. These compounds are found in various foods and many are carcinogenic or are suspected carcinogens. Cured meats can contain nitrosamines because meats contain amines and can react during cooking with sodium nitrite that is added as a preservative. (NCI05)]
4-Nitroquinoline N-oxide	NCIT_C29802
Childhood T Lymphoblastic Lymphoma	NCIT_C7210	[A T lymphoblastic lymphoma that occurs during childhood.]
Childhood T Lymphoblastic Leukemia/Lymphoma	NCIT_C5640	[A T lymphoblastic leukemia/lymphoma that occurs during childhood.]
Childhood Lymphoblastic Lymphoma	NCIT_C9124	[A lymphoblastic lymphoma occurring in children.]
T Lymphoblastic Lymphoma	NCIT_C6919	[The most frequent type of lymphoblastic lymphoma. It comprises approximately 85-90% of cases. It is more frequently seen in adolescent males. It frequently presents with a mass lesion in the mediastinum. Pleural effusions are common. (WHO, 2001)]
Childhood Primary Cutaneous Anaplastic Large Cell Lymphoma	NCIT_C7211	[An anaplastic large cell lymphoma that occurs during childhood and is limited to the skin at the time of diagnosis.]
Primary Cutaneous Anaplastic Large Cell Lymphoma	NCIT_C6860	[An anaplastic large cell lymphoma limited to the skin at the time of diagnosis. Most patients present with solitary or localized skin lesions, which may be tumors, nodules or papules. The t(2;5) translocation that is present in many cases of systemic anaplastic large cell lymphoma, is not found in this disease. (WHO, 2001)]
Childhood Anaplastic Large Cell Lymphoma	NCIT_C5636	[An anaplastic large cell lymphoma that occurs during childhood.]
Refractory T Lymphoblastic Lymphoma	NCIT_C7227	[T Lymphoblastic lymphoma that does not respond to treatment.]
Refractory Aggressive Non-Hodgkin Lymphoma	NCIT_C156233	[An aggressive non-Hodgkin lymphoma that is resistant to treatment.]
Refractory T-Cell Non-Hodgkin Lymphoma	NCIT_C8664	[T-cell non-Hodgkin lymphoma resistant to treatment.]
Refractory T Lymphoblastic Leukemia/Lymphoma	NCIT_C8696	[T-lymphoblastic leukemia/lymphoma resistant to treatment]
Refractory Mature B-Cell Non-Hodgkin Lymphoma	NCIT_C7228	[Mature B-cell non-Hodgkin lymphoma that does not respond to treatment.]
Refractory B-Cell Non-Hodgkin Lymphoma	NCIT_C8842	[B-cell non-Hodgkin lymphoma that is resistant to treatment.]
Blastoid Variant Mantle Cell Lymphoma	NCIT_C7229	[An aggressive mantle cell lymphoma characterized by the presence of neoplastic B-lymphocytes resembling lymphoblasts.]
Mantle Cell Lymphoma	NCIT_C4337	[An aggressive, usually diffuse non-Hodgkin lymphoma composed of small to medium sized B-lymphocytes (centrocytes). Most patients present with advanced stage disease with lymphadenopathy, hepatosplenomegaly, and bone marrow involvement. The gastrointestinal tract is the most commonly affected extranodal site by this type of non-Hodgkin lymphoma. The vast majority of cases express the t(11;14)(q13;q32) resulting in the rearrangement of the BCL-1 gene and the overexpression of cyclin D1 mRNA.]