Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Work-up	NCIT_C85833	[A complete diagnostic examination of a patient including history taking, physical examinations, laboratory tests, and medical imaging.]
ADCS-ADL MCI - Talk Within 24 Hours After Reading	NCIT_C106920	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) If yes, did subject usually talk about what he or she read 1-24 hours after reading?]
ADCS-ADL MCI Questionnaire Question	NCIT_C106672	[A question associated with the ADCS-ADL MCI questionnaire.]
ADCS-ADL MCI - Watch Television	NCIT_C106921	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) In the past 4 weeks, did subject watch television?]
ADCS-ADL MCI - Select or Ask for Programs or Show	NCIT_C106922	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) If yes, did subject usually select or ask for different programs or his or her favorite show?]
ADCS-ADL MCI - Talk About Content of Program While Watching	NCIT_C106923	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) If yes, did subject usually talk about the content of a program while watching it?]
ADCS-ADL MCI - Talk About Content of Program After Watching Within a Day	NCIT_C106924	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) If yes, did subject talk about the content of a program within a day (24 hours) after watching it?]
Hsp90 Antagonist KW-2478	NCIT_C69139	[An agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Although the mechanism of action remains to be fully elucidated, Hsp90 antagonist KW-2478 appears to inhibit Hsp90, resulting in impaired signal transduction, inhibition of cell proliferation, and the induction of apoptosis in tumor cells. HSP90 is a molecular chaperone that plays a key role in the conformational maturation of oncogenic signaling proteins, such as HER2/ERBB2, AKT, RAF1, BCR-ABL, and mutated p53, as well as many other molecules that are important in cell cycle regulation or immune responses.]
HSP90 Inhibitor	NCIT_C156880	[Any agent that inhibits heat shock protein (Hsp) 90.]
ADCS-ADL MCI - Go Shopping At a Store	NCIT_C106925	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) In the past 4 weeks, did subject ever go shopping at a store?]
ADCS-ADL MCI - Select Correct Items Without Help	NCIT_C106926	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) If yes, did subject usually select correct items without supervision or help?]
ADCS-ADL MCI - Pay for Items on His or Her Own	NCIT_C106927	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) If yes, did subject usually pay for items on his or her own?]
ADCS-ADL MCI - Left on His or Her Own	NCIT_C106928	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) In the past 4 weeks, was subject ever left on his or her own?]
ADCS-ADL MCI - Left Away From Home Longer Than 15 Minutes	NCIT_C106929	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) If yes, was subject left away from home, for 15 minutes or longer, during the day?]
Childhood Classic Hodgkin Lymphoma	NCIT_C69142	[A classic Hodgkin lymphoma that occurs during childhood.]
Childhood Hodgkin Lymphoma	NCIT_C7714	[Hodgkin lymphoma occurring in childhood.]
Classic Hodgkin Lymphoma	NCIT_C7164	[A monoclonal B-cell lymphoproliferation in the vast majority of cases. It is characterized by a bimodal age distribution (15-30 years of life and late life). Epstein-Barr virus has been postulated to play a role in the pathogenesis of classic Hodgkin lymphoma. Morphologically, it is characterized by the presence of Reed-Sternberg cells and mononuclear Hodgkin cells. The Reed-Sternberg and mononuclear Hodgkin cells are CD30 positive in nearly all cases and CD15 positive in the majority of cases. Four histologic subtypes have been distinguished: lymphocyte-rich, nodular sclerosis, mixed cellularity, and lymphocyte-depleted classic Hodgkin lymphoma.]
MEK Inhibitor AZD8330	NCIT_C69143	[An orally active, selective MEK inhibitor with potential antineoplastic activity. MEK inhibitor AZD8330 specifically inhibits mitogen-activated protein kinase kinase 1 (MEK or MAP/ERK kinase1), resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation. MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth; constitutive activation of this pathway has been implicated in many cancers.]
Mitogen-Activated Protein Kinase Kinase Inhibitor	NCIT_C69145	[Any substance that inhibits mitogen-activated protein kinase kinase (MEK), an enzyme that catalyzes the addition of a phosphate group to a mitogen-activated protein kinase. Inhibition of mitogen-activated protein kinase kinase results in the inhibition of cell proliferation.]
Antineoplastic Enzyme Inhibitor	NCIT_C129825	[Any agent that specifically inhibits a particular enzyme that is overexpressed and/or mutated in cancer cell pathways. Antineoplastic enzyme inhibitors specifically target tumor cells by targeting enzymes that are not normally expressed or are minimally expressed in normal, healthy tissues.]