Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Recurrent Grade III Lymphomatoid Granulomatosis	NCIT_C69144
Grade III Lymphomatoid Granulomatosis	NCIT_C7933	[Lymphomatoid granulomatosis characterized by the presence of aggregates of neoplastic large B-lymphocytes, usually admixed with pleomorphic and Hodgkin-like cells, in a background of chronic inflammation. Necrotic changes are present and are usually extensive. Grade III lymphomatoid granulomatosis should be approached clinically as a subtype of diffuse large B-cell lymphoma.]
Recurrent Lymphomatoid Granulomatosis	NCIT_C7934
Recurrent Aggressive Non-Hodgkin Lymphoma	NCIT_C156232	[An aggressive non-Hodgkin lymphoma that has recurred after a period of remission.]
Recurrent Diffuse Large B-Cell Lymphoma	NCIT_C8852	[The reemergence of diffuse large B-cell lymphoma after a period of remission.]
Recurrent EBV-Related Lymphoma	NCIT_C147863	[The reemergence of EBV-related lymphoma after a period of remission.]
Protein Kinase Inhibitor	NCIT_C1404	[Any substance that inhibits protein kinase, an enzyme that catalyzes the addition of a phosphate group to a protein and is active in many diverse signaling pathways.]
Mast Cell Stabilizer TF002	NCIT_C69146	[A small molecule with mast cell stabilizing activity. Mast cell stabilizer TF002 inhibits the formation of lipid rafts of mast cell membranes that contain the signaling machinery which triggers the release of mast cell allergic and inflammatory mediators. Inhibition of lipid raft assembly by this agent results in mast cell stabilization, preventing mast cell degranulation and the release of the inflammatory mediators involved in type I allergic reactions (histamine, leukotrienes, prostaglandins, and cytokines). The assembly of the signaling machinery in mast cell lipid rafts, specialized membrane microdomains rich in cholesterol and sphingolipids, is initiated by IgE binding to its receptor on the mast cell surface; subsequently, allergens crosslink with the IgE/receptor complex and other proteins and lipids are recruited into the signaling machinery.]
Mast Cell Stabilizer	NCIT_C29714
Femtometer	NCIT_C69147	[A metric unit of length equal to one quadrillionth of a meter (10E-15 meter).]
Unit of Length	NCIT_C42578	[An indication of the type of unit of measure being used to express a length or distance.]
Picometer	NCIT_C69148	[A metric unit of length equal to one trillionth of a meter (10E-12 meter).]
Microsecond	NCIT_C69149	[A unit of time equal to one millionth of a second.]
D-methionine Formulation MRX-1024	NCIT_C69140	[A proprietary oral formulation of D-methionine with antioxidant and antimucositis activities. D-methionine formulation MRX-1024 may selectively protect the oral mucosa from the toxic effects of chemotherapy and radiation therapy without compromising antitumor activity. D-methionine may be converted into the L- isomer in vivo, particularly in instances of L-methionine deprivation; both isomers have antioxidant activity which may be due, in part, to their sulfur moieties and chelating properties. L-methionine, an essential amino acid, also may help to maintain the ratio of reduced glutathione to oxidized glutathione in cells undergoing oxidative stress and may provide a source of L-cysteine for glutathione synthesis.]
Agent Affecting Integumentary System	NCIT_C78284	[An agent that exerts a physiologic effect on any anatomic entity that is part of the integumentary system, including skin, nails and hair.]
Antioxidant	NCIT_C275	[A group of organic or inorganic substances capable of preventing the genotoxic and carcinogenic effects of free-radical compounds. Antioxidants bind to and neutralize ('scavenge') free radicals, thereby transforming them into non-toxic compounds and blocking their genotoxic and carcinogenic effects. This class of agents includes the vitamins C and E, the carotenoids, and selenium. Organic antioxidants are found in high concentrations in fruits, seeds and vegetables. (NCI04)]
Curator	NCIT_C69141	[The person in charge of the care and superintendence of something, especially a collection.]
Person	NCIT_C25190	[A human being.]
ADCS-ADL MCI - Travel Outside Home	NCIT_C106910	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) In the past 4 weeks, did subject get around (or travel) outside of his or her home?]
ADCS-ADL MCI - Description of Optimal Performance of Travelling Outside Home	NCIT_C106911	[Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory, MCI (ADCS-ADL MCI) If yes, which best describes his or her optimal performance.]