Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Distress over Family Problem with Family Health Issues	NCIT_C107178	[A question about an individual's distress related to their family problems dealing with family health issues.]
Myositis, CTCAE 5.0	NCIT_C146787	[A disorder characterized by inflammation involving the skeletal muscles.]
Musculoskeletal and Connective Tissue Disorders, CTCAE	NCIT_C143175
Distress over Emotional Problem with Depression	NCIT_C107179	[A question about an individual's distress related to their emotional problems with depression.]
Unresectable Leiomyosarcoma	NCIT_C132147	[A leiomyosarcoma which is not amenable to surgical resection.]
Unresectable Sarcoma	NCIT_C148331	[A sarcoma which is not amenable to surgical resection.]
Allogeneic HLA-A2/4-1BB ligand-expressing Melanoma Vaccine	NCIT_C107169	[An allogeneic melanoma cell vaccine derived from a cell line with high expression of melanoma associated antigens and genetically modified to express both HLA-A2 and 4-1BB ligand, with potential immunostimulating and antineoplastic activities. Upon administration, the 4-1BB ligand of the allogeneic HLA-A2/4-1BB ligand-expressing melanoma vaccine binds to 4-1BB on activated T-lymphocytes, which induces a strong immune response against HLA-A2 positive melanoma cells.]
Unresectable Liposarcoma	NCIT_C132148	[A liposarcoma which is not amenable to surgical resection.]
PADI2 Gene	NCIT_C132149	[This gene plays a role in post-translational deimination of proteins.]
Cyclin-A2	NCIT_C20956	[Cyclin-A2 (432 aa, ~49 kDa) is encoded by the human CCNA2 gene. This protein is involved in the regulation of both the cell cycle and mitosis.]
Cyclin	NCIT_C17349	[A non-enzymatic regulatory protein that is critical during the cell cycle. The cyclin family members complex with other proteins to modulate the protein kinase activity of the cell.]
Cyclin Gene	NCIT_C25840	[These genes encode member proteins of the highly conserved cyclin family. They are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. (From RefSeq Summary and NCI)]
G1/S-Specific Cyclin-E2	NCIT_C20959	[G1/S-specific cyclin-E2 (404 aa, ~47 kDa) is encoded by the human CCNE2 gene. This protein plays a role in cell cycle checkpoint regulation between the G1 and S phases.]
BAG1 Gene	NCIT_C20952	[This gene plays a role in signal transduction and is involved in the negative regulation of apoptosis.]
BAG Family Molecular Chaperone Regulator 1	NCIT_C20953	[BAG family molecular chaperone regulator 1 (345 aa, ~39 kDa) is encoded by the human BAG1 gene. This protein plays a role in the regulation of apoptosis and the inhibition of HSP70 chaperone activity.]
SH3KBP1 Gene	NCIT_C132140	[This gene is involved in the regulation of protein-protein interactions in signaling pathways.]
BRS3 Gene	NCIT_C20954	[This gene is involved in the regulation of metabolic and endocrine processes required for energy storage and consumption.]
SH3KBP1 wt Allele	NCIT_C132141	[Human SH3KBP1 wild-type allele is located in the vicinity of Xp22.12 and is approximately 354 kb in length. This allele, which encodes SH3 domain-containing kinase-binding protein 1, plays a role in adaptor signaling protein activity.]
EGF Receptor Downregulation by CBL Pathway	NCIT_C39016
Bombesin Receptor Subtype-3	NCIT_C20955	[Bombesin receptor subtype-3 (399 aa, ~44 kDa) is encoded by the human BRS3 gene. This protein is involved in a number of G protein-coupled receptor signaling pathways.]