Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Damage Induced Long Noncoding RNA	NCIT_C132163	[Damage induced long noncoding RNA (~1 kb) is encoded by the human DINOL gene. This non-coding RNA is involved in p53-dependent gene expression, cell cycle arrest, and apoptosis in response to DNA damage.]
National Cancer Institute Community Oncology Research Program	NCIT_C132164	[A national network of investigators, cancer care providers, academic institutions, and other organizations that conduct multi-site cancer clinical trials and studies in diverse populations in community-based healthcare systems across the United States and Puerto Rico.]
Immune Checkpoint Functional Assay	NCIT_C132165	[Various bioassays designed to measure levels of key regulatory molecules, such as PD-1 (PDCD1), CTLA-4, GITR (TNFRSF18), 4-1BB (TNFRSF9), OX40 (TNFRSF4), and TIGIT, that mediate immune checkpoint receptor pathways or assays to measure proliferation, expression of cell surface activation markers, and cytokine expression induced by these pathways.]
PI3K Inhibitor GDC0077	NCIT_C132166	[An orally available inhibitor of phosphatidylinositol 3-kinase (PI3K), with potential antineoplastic activity. PI3K inhibitor GDC0077 binds to and inhibits various members of the PI3K family, including activating mutations in the catalytic alpha isoform PIK3CA. PI3K inhibition prevents the activation of the PI3K-mediated signaling pathway and results in the inhibition of growth and survival of PI3K-overexpressing tumor cells. Dysregulation of the PI3K signaling pathway is frequently associated with tumorigenesis and tumor resistance to a variety of antineoplastic agents and radiotherapy. PIK3CA, which encodes the p110-alpha catalytic subunit of the class I PI3K, is frequently mutated in a variety of cancer cell types and plays a key role in cancer cell growth and invasion.]
ASB2 Gene	NCIT_C132167	[This gene is involved in substrate recognition of ubiquitin ligase complexes.]
ASB2 wt Allele	NCIT_C132168	[Human ASB2 wild-type allele is located in the vicinity of 14q32.12 and is approximately 43 kb in length. This allele, which encodes ankyrin repeat and SOCS box protein 2, plays a role in promoting the ubiquitination of substrate proteins.]
Child-Pugh Class C14	NCIT_C146799	[A total score of 14 for hepatic function, corresponding to class C in the Child-Pugh classification.]
Child-Pugh Class C	NCIT_C113694	[Child-Pugh score indicating one-year survival of 45% in patients with chronic liver disease and cirrhosis. This score is determined by the study of the following five factors: bilirubin, albumin, international normalized ratio, presence and degree of ascites, and presence and degree of encephalopathy.]
Prostate Cancer Associated Transcript 1	NCIT_C132160	[Prostate cancer associated transcript 1 (~2 kb) is encoded by the human PCAT1 gene. This non-coding RNA may play a role in tumorigenesis.]
Child-Pugh Class A6	NCIT_C146791	[A total score of 6 for hepatic function, corresponding to class A in the Child-Pugh classification.]
Child-Pugh Class B7	NCIT_C146792	[A total score of 7 for hepatic function, corresponding to class B in the Child-Pugh classification.]
Child-Pugh Class B	NCIT_C113692	[Child-Pugh score indicating one-year survival of 80% in patients with chronic liver disease and cirrhosis. This score is determined by the study of the following five factors: bilirubin, albumin, international normalized ratio, presence and degree of ascites, and presence and degree of encephalopathy.]
Child-Pugh Class B8	NCIT_C146793	[A total score of 8 for hepatic function, corresponding to class B in the Child-Pugh classification.]
Child-Pugh Class B9	NCIT_C146794	[A total score of 9 for hepatic function, corresponding to class B in the Child-Pugh classification.]
Child-Pugh Class C10	NCIT_C146795	[A total score of 10 for hepatic function, corresponding to class C in the Child-Pugh classification.]
Child-Pugh Class C11	NCIT_C146796	[A total score of 11 for hepatic function, corresponding to class C in the Child-Pugh classification.]
Child-Pugh Class C12	NCIT_C146797	[A total score of 12 for hepatic function, corresponding to class C in the Child-Pugh classification.]
Child-Pugh Class C13	NCIT_C146798	[A total score of 13 for hepatic function, corresponding to class C in the Child-Pugh classification.]
Stage I Vulvar Cancer AJCC v6	NCIT_C7854	[Stage I includes: T1, N0, M0. T1: Tumor confined to the vulva or vulva and perineum, 2cm or less in greatest dimension. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th ed.). - 2003]
Vulvar Cancer by AJCC v6 Stage	NCIT_C90345	[A term that refers to the staging of vulvar carcinoma according to the American Joint Committee on Cancer, 6th edition.]