Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Sudden Death	NCIT_C107103	[An unexpected death without warning.]
Pseudophedrine/Loratadine	NCIT_C29392
Stage III Mycosis Fungoides AJCC v7	NCIT_C7800	[Stage III includes: (T4, N0-2, M0, B0-1); IIIA (T4, N0-2, M0, B0); IIIB (T4, N0-2, M0, B1). T4: Confluence of erythema covering 80% or more of body surface area. N0: No clinically abnormal peripheral lymph nodes; biopsy not required. N1: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN0-2. N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3. M0: No visceral organ involvement. B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells). B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2. (AJCC 7th ed.)]
Mycosis Fungoides by AJCC v7 Stage	NCIT_C141143	[A term that refers to the staging of mycosis fungoides, following the rules of the TNM AJCC v7 classification system.]
NID2 Gene	NCIT_C107104	[This gene plays a structural role in the basement membrane.]
Psyllium	NCIT_C29393
Stage IV Cutaneous T-Cell Non-Hodgkin Lymphoma	NCIT_C7801
Stage IV	NCIT_C27971	[Cancer that has spread to distant anatomic sites beyond its original site of growth.]
NID2 wt Allele	NCIT_C107105	[Human NID2 wild-type allele is located in the vicinity of 14q22.1 and is approximately 64 kb in length. This allele, which encodes nidogen-2 protein, is involved inmaintaining the structure of the basement membrane.]
Pyrazoloacridine	NCIT_C29394
Stage IV Mycosis Fungoides AJCC v7	NCIT_C7802	[Stage IV includes: IVA1 (T1-4, N0-2, M0, B2); IVA2 (T1-4, N3, M0, B0-2); IVB (T1-4, N0-3, M1, B0-2). T1: Limited patches, papules, and/or plaques covering less than 10% of the skin surface. May further stratify into T1a (patch only) vs. T1b (plaque +/- patch). T2: Patches, papules, or plaques covering 10% or more of the skin surface. May further stratify into T2a (patch only) vs. T2b (plaque +/- patch). T3: One or more tumors (equal or greater than 1 cm diameter). T4: Confluence of erythema covering 80% or more of body surface area. N0: No clinically abnormal peripheral lymph nodes; biopsy not required. N1: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 1 or NCI LN0-2. N2: Clinically abnormal peripheral lymph nodes; histopathology Dutch grade 2 or NCI LN3. N3: Clinically abnormal peripheral lymph nodes; histopathology Dutch grades 3-4 or NCI LN4; clone positive or negative. M0: No visceral organ involvement. M1: Visceral involvement (must have pathology confirmation and organ involved should be specified). B0: Absence of significant blood involvement: 5% or less of peripheral blood lymphocytes are atypical (Sezary cells). B1: Low blood tumor burden: more than 5% of peripheral blood lymphocytes are atypical (Sezary cells) but does not meet the criteria of B2. B2: High blood tumor burden: 1000/microL Sezary cells or more with positive clone. (AJCC 7th ed.)]
Nidogen-2	NCIT_C107106	[Nidogen-2 (1375 aa, ~151 kDa) is encoded by the human NID2 gene. This protein plays a role in both basement membrane structure and cell adhesion.]
EGF-Like Domain	NCIT_C13937	[A sequence of about thirty to forty amino-acid residues long found in the sequence of epidermal growth factor (EGF) has been shown to be present, in a conserved form, in a large number of other, mostly animal proteins. The list of proteins currently known to contain one or more copies of an EGF-like pattern is large and varied. The functional significance of EGF domains in what appear to be unrelated proteins is not yet clear. However, a common feature is that these repeats are found in the extracellular domain of membrane-bound proteins or in proteins known to be secreted (exception: prostaglandin G/H synthase). The EGF domain includes six cysteine residues which have been shown (in EGF) to be involved in disulfide bonds. The main structure is a two-stranded beta-sheet followed by a loop to a C-terminal short two-stranded sheet. Subdomains between the conserved cysteines vary in length. (InterPro IPR006209)]
Extracellular Matrix	NCIT_C13232	[The extracellular matrix is a network of fibers that hold cells together. It is found within the extracellular space and in association with the basement membrane of the cell surface. It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere. It is broken down during normal physiological and disease processes such as bone remodeling, embryogenesis, cancer, and arthritis.]
Pyrazinamide	NCIT_C29395	[A synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular bacilli (unaffected by other drugs) by an unknown mechanism of action. Its bactericidal action is dependent upon the presence of bacterial pyrazinamidase, which removes the amide group to produce active pyrazinoic acid. Pyrazinamide is an important component of multidrug therapy for tuberculosis. (NCI04)]
Antitubercular Agent	NCIT_C280	[Any agent that is active against Mycobacterium tuberculosis and can be used in the treatment of or in the prevention of tuberculosis.]
ACLY Gene	NCIT_C107107	[This gene is involved in acetyl-CoA metabolism.]
MANF wt Allele	NCIT_C54330	[Human MANF wild-type allele is located in the vicinity of 3p21.1 and is approximately 4 kb in length. This allele, which encodes mesencephalic astrocyte-derived neurotrophic factor protein, plays a role in both the modulation of GABA neurotransmission and the mediation of dopaminergic neuron survival.]
3p21.1	NCIT_C14004	[A chromosome band present on 3p]
3: 51397518-51401815	NCIT_C41719	[Physical location of ARMET_Gene]