Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Acetaminophen/Phenylephrine-containing Formulation	NCIT_C29526	[A commercial combination preparation, by Johnson and Johnson, containing acetaminophen and pseudoephedrine hydrochloride used to relieve symptoms of cold and flu. Acetaminophen exerts analgesic and antipyretic actions by inhibiting prostaglandin synthesis. Pseudoephedrine hydrochloride, a sympathomimetic agent, acts as a decongestant by inducing vasoconstriction mediated through alpha-adrenergic receptors, thereby reducing blood flow which decreases swelling and prevents and relieves nasal and sinus congestion.]
U-90	NCIT_C29527
Diphenhydramine/Phenylephrine-containing Syrup	NCIT_C29517	[A cough and cold syrup containing the first-generation antihistamine diphenhydramine hydrochloride and the decongestant phenylephrine hydrochloride. Diphenhydramine blocks the effects of histamine, thereby preventing symptoms such as sneezing and itchy, watery eyes, runny nose and sore throat. In addition, this agent causes drowsiness and can be used as a sleep aid. Phenylephrine, a sympathomimetic agent, acts as a decongestant by inducing vasoconstriction mediated via alpha-adrenergic receptors. This reduces blood flow, decreases swelling and prevents nasal and sinus congestion.]
Grade 5 Skin Ulceration, CTCAE	NCIT_C146546	[Death]
Triaminic Syrup	NCIT_C29518	[Any of the commercial combination preparations, by Novartis, that is taken orally as syrup containing all or a combination of the following agents: the analgesic antipyretic acetaminophen, the antihistamine chlorpheniramine maleate, the antitussive dextromethorphan hydrobromide and the decongestant pseudoephedrine hydrochloride. The particular combination depends on the symptoms that need to be treated such as cough, congestion, fever, allergy and sore throat. Acetaminophen exerts its actions by inhibiting prostaglandin synthesis. Chlorpheniramine maleate blocks the effects of histamine. Dextromethorphan hydrobromide raises the threshold for coughing in the cough center. Pseudoephedrine, a sympathomimetic agent, causes vasoconstriction mediated through alpha-adrenergic receptors, thereby reducing blood flow which decreases swelling and prevents nasal and sinus congestion.]
Grade 5 Sleep Apnea, CTCAE	NCIT_C146547	[Death]
Triamterene	NCIT_C29519	[A pteridine derivative with potassium-sparing diuretic property. Triamterene blocks the sodium-potassium exchange pump (Na-K-ATPase) in the luminal membrane of principal cells in the late distal tubule, cortical collecting tubule and collecting duct in the kidney. This reversible inhibition of the electrogenic sodium transport decreases the lumen-negative transepithelial potential difference and thus reduces the driving force for K+ movement into the tubular lumen resulting in the inhibition of sodium reabsorption in exchange for K+ and H+.]
Grade 5 Small Intestinal Anastomotic Leak, CTCAE	NCIT_C146548	[Death]
Grade 5 Small Intestinal Mucositis, CTCAE	NCIT_C146549	[Death]
Grade 5 Sinus Disorder, CTCAE	NCIT_C146540	[Death]
Grade 5 Sinusitis, CTCAE	NCIT_C146541	[Death]
Grade 5 Sinusoidal Obstruction Syndrome, CTCAE	NCIT_C146542	[Death]
Grade 5 Skin and Subcutaneous Tissue Disorders - Other, Specify, CTCAE	NCIT_C146543	[Death]
Grade 5 Skin Induration, CTCAE	NCIT_C146544	[Death]
Grade 5 Skin Infection, CTCAE	NCIT_C146545	[Death]
Undecylenic Acid	NCIT_C29530	[A natural or synthetic fungistatic fatty acid, antifungal Undecylenic Acid is used topically as a zinc salt in various creams against fungal infections, eczemas, ringworm, and other cutaneous conditions. The zinc provides an astringent action, reducing rawness and irritation.]
Urea	NCIT_C29531	[A nitrogenous compound containing a carbonyl group attached to two amine groups with osmotic diuretic activity. In vivo, urea is formed in the liver via the urea cycle from ammonia and is the final end product of protein metabolism. Administration of urea elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain, cerebrospinal fluid and eye, into interstitial fluid and plasma, thereby decreasing pressure in those tissues and increasing urine outflow.]
Atropine/Hyoscyamine/Methenamine/Methylene Blue/Phenyl Salicylate/Benzoic Acid	NCIT_C29532	[A combination preparation of methenamine, methylene blue, benzoic acid, phenyl salicylate, atropine sulfate, and hyoscyamine sulfate, with anti-inflammatory, antispasmodic and analgesic properties. Methenamine hydrolyzes into formaldehyde in acidic urine, thereby providing mild antiseptic effect. Methylene blue also exerts mild antiseptic activity and may inhibit bacterial proliferation. Benzoic acid exerts mild antibacterial and antifungal activities and helps maintain an acidic pH in the urine necessary for the degradation of methenamine to formaldehyde. Phenyl salicylate exerts mild analgesic, antipyretic and anti-inflammatory actions. Atropine sulfate and hyoscyamine sulfate are antimuscarinic agents that prevent smooth muscle spasms by antagonizing actions of acetylcholine. Urised is used for the relief of symptoms associated with urinary tract infections or diagnostic procedures.]
VAC0P	NCIT_C29533
VATH	NCIT_C29534