Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Valacyclovir Hydrochloride	NCIT_C29535	[The hydrochloride salt of valacyclovir. Valacyclovir is an acyclovir prodrug that, after metabolization, inhibits viral DNA replication. It is used in the management of herpes simplex and varicella zoster infections, as well as prophylactically for human cytomegalovirus infections.]
DNA Polymerase Inhibitor	NCIT_C29575	[Any substance that inhibits DNA polymerase, an enzyme that catalyzes the addition of deoxyribonucleotide residues to the end of a DNA molecule. Inhibition of DNA polymerase causes an inhibition of DNA synthesis and results in cell cycle arrest.]
Valproic Acid	NCIT_C29536	[A synthetic derivative of propylpentanoic acid with antiepileptic properties and potential antineoplastic and antiangiogenesis activities. In epilepsy, valproic acid appears to act by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain. This agent's antitumor and antiangiogenesis activities may be related to the inhibition of histone deacetylases and nitric oxide synthase, which results in the inhibition of nitric oxide synthesis. (NCI04)]
Variconazole	NCIT_C29537
Petrolatum	NCIT_C29538
Uniroyal Compound-38	NCIT_C29528	[A second generation non-nucleoside reverse transcriptase inhibitor derivative of oxathiin carboxanilide. Uniroyal compound 38 has activity against a wide range of biologically diverse laboratory and clinical strains of HIV-1 but is inactive against HIV-2.]
Non-nucleoside Reverse Transcriptase Inhibitor	NCIT_C97453	[A substance structurally unlike a nucleoside molecule that is capable of inhibiting the function of a reverse transcriptase. These compounds do not bind to the active site of the polymerase but in a less conserved pocket near the active site, causing a distortion in the shape of the active site and resulting in inhibition of enzymatic function, chain termination, and inhibition of viral replication.]
Grade 5 Salivary Duct Inflammation, CTCAE	NCIT_C146535	[Death]
UVB	NCIT_C29529
Grade 5 Salivary Gland Infection, CTCAE	NCIT_C146536	[Death]
Grade 5 Scrotal Infection, CTCAE	NCIT_C146537	[Death]
Grade 5 Sepsis, CTCAE	NCIT_C146538	[Death]
Grade 5 Shingles, CTCAE	NCIT_C146539	[Death]
Grade 5 Respiratory Failure, CTCAE	NCIT_C146530	[Death]
Grade 5 Respiratory, Thoracic and Mediastinal Disorders - Other, Specify, CTCAE	NCIT_C146531	[Death]
Grade 5 Retroperitoneal Hemorrhage, CTCAE	NCIT_C146532	[Death]
Grade 5 Reversible Posterior Leukoencephalopathy Syndrome, CTCAE	NCIT_C146533	[Death]
Grade 5 Rhabdomyolysis, CTCAE	NCIT_C146534	[Death]
Venlafaxine Hydrochloride	NCIT_C29540	[A synthetic ethyl-cyclohexanol derivative used for the treatment of depression, Venlafaxine Hydrochloride is metabolized to O-desmethylvenlafaxine, which potentiates CNS activity. Both venlafaxine and its active metabolite inhibit neuronal reuptake of norepinephrine, dopamine, and serotonin. (NCI04)]
Vicodin	NCIT_C29541