Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Oral Cavity Neoplasm	NCIT_C7606	[A benign or malignant neoplasm that affects the oral cavity.]
Oral Neoplasm	NCIT_C8989	[A benign or malignant neoplasm involving the oral cavity and/or the lips.]
Benign Oral Neoplasm	NCIT_C7608	[A non-metastasizing neoplasm that arises from the oral cavity or the lips.]
Benign Neoplasm	NCIT_C3677	[A neoplasm which is characterized by the absence of morphologic features associated with malignancy (severe cytologic atypia, tumor cell necrosis, and high mitotic rate). Benign neoplasms remain confined to the original site of growth and do not metastasize to other anatomic sites.]
Untreated Chronic Lymphocytic Leukemia	NCIT_C132015	[A finding of chronic lymphocytic leukemia that has not been treated.]
Untreated Hematopoietic and Lymphoid Cell Neoplasm	NCIT_C115907	[A finding of hematopoietic or lymphoid cell neoplasm that has not been treated.]
C-SSRS Already Enrolled Subjects - Number of Actual Suicide Attempts (Since Study Start)	NCIT_C107059	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) Total number of actual attempts. (Since Study Start).]
C-SSRS Already Enrolled Subjects Questionnaire Question	NCIT_C106676	[A question associated with the C-SSRS Already Enrolled Subjects questionnaire.]
Untreated Small Lymphocytic Lymphoma	NCIT_C132016	[A finding of small lymphocytic lymphoma that has not been treated.]
Anti-AXL Monoclonal Antibody-MMAE Conjugate	NCIT_C132017	[An antibody-drug conjugate (ADC), consisting of a human monoclonal antibody directed against AXL receptor tyrosine kinase (AXL; UFO) and conjugated, through a protease-cleavable linker, to the cytotoxic agent monomethyl auristatin E (MMAE), with potential antineoplastic activity. Upon administration, the monoclonal antibody moiety of HuMax-AXL-ADC binds to AXL, which is expressed on the surfaces of a variety of cancer cell types. Upon endocytosis and enzymatic cleavage, MMAE is released into the tumor cell cytosol, where it binds to tubulin and inhibits tubulin polymerization; this may result in G2/M phase arrest and apoptosis. AXL, a member of the TAM (TYRO3, AXL and MER) family of receptor tyrosine kinases and overexpressed by many tumor cell types, plays a key role in tumor cell proliferation, survival, invasion and metastasis; its expression is associated with drug resistance and poor prognosis.]
MYC Gene Rearrangement	NCIT_C132018	[A molecular abnormality indicating rearrangement of the MYC gene.]
Gene Rearrangement Abnormality	NCIT_C133155	[A molecular abnormality characterized by rearrangement of a gene sequence that results in either aberrant gene expression or the translation of a novel protein.]
MYC Gene	NCIT_C16887	[This gene plays a role in cell cycle progression and apoptosis. Cytogenetic aberrations in the gene are involved in cellular transformation and are associated with a variety of hematopoietic tumors, leukemias and lymphomas.]
BCL2 Gene Rearrangement	NCIT_C132019	[A molecular abnormality indicating rearrangement of the BCL2 gene.]
Chromosome 18	NCIT_C13213	[The designation for each member of the eighteenth largest human autosomal chromosome pair. Chromosome 18 spans about 76 million base pairs and represents about 2.5% of the total DNA in normal diploid cells.]
G-Protein Coupled Receptor 39	NCIT_C29641	[G-protein coupled receptor 39 (453 aa, ~51 kDa) is encoded by the human GPR39 gene. This protein is involved in the activation of second messenger signaling.]
KiSS-1 Receptor	NCIT_C29643	[KiSS-1 receptor (398 aa, ~43 kDa) is encoded by the human KISS1R gene. This protein plays a role in the onset of puberty and the suppression of tumor metastasis.]
pH Homeostasis	NCIT_C29644	[pH homeostasis is one of numerous control systems that are involved in keeping the body's internal milieu consistent within a narrow range of variation and are important to the continuation of life. Important homeostatic mechanisms in the maintenance of blood pH include the buffering action of bicarbonate, and the actions of the renal-respiratory system. (from NCI)]
T5 Stage Finding	NCIT_C132010	[An antiquated primary tumor finding term that refers to colorectal cancer which has spread by direct extension beyond the immediately adjacent organs or tissues. (AJCC 1st Ed.)]
Generic Primary Tumor TNM Finding	NCIT_C48885