Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
ICFW Mouse	NCIT_C15001
Cereblon E3 Ubiquitin Ligase Modulating Agent CC-92480	NCIT_C146660	[A modulator of the E3 ubiquitin ligase complex containing cereblon (CRL4-CRBN E3 ubiquitin ligase), with potential immunomodulating and antineoplastic activities. Upon administration, cereblon E3 ubiquitin ligase modulating agent CC-92480 specifically binds to cereblon (CRBN), thereby affecting the ubiquitin E3 ligase activity, and targeting certain substrate proteins for ubiquitination. This induces proteasome-mediated degradation of certain transcription factors, some of which are transcriptional repressors in T-cells. This leads to modulation of the immune system, including activation of T-lymphocytes, and downregulation of the activity of other proteins, some of which play key roles in the proliferation of certain cancer cell types. CRBN, the substrate recognition component of the CRL4-CRBN E3 ubiquitin ligase complex, plays a key role in the ubiquitination of certain proteins.]
C-SSRS Already Enrolled Subjects - Deterrents to Most Severe Ideation (Prior to Study Entry)	NCIT_C107052	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) Are there things-anyone or anything (e.g., family, religion, pain of death) that stopped you from wanting to die or acting on thoughts of committing suicide? (Prior to Study Entry).]
CFW Mouse	NCIT_C15002
Lymphoblasts 20 Percent or More of Bone Marrow Nucleated Cells	NCIT_C146661	[A semi-quantitative microscopic finding indicating that 20 percent or more of the nucleated cells in a bone marrow sample are immature mononuclear cells of lymphoid origin.]
Blasts 20 Percent or More of Bone Marrow Nucleated Cells	NCIT_C36214	[A semi-quantitative microscopic finding indicating that 20 percent or more of the nucleated cells in a bone marrow sample are immature mononuclear cells.]
Lymphoblasts 5 Percent or More of Bone Marrow Nucleated Cells	NCIT_C142103	[A semi-quantitative microscopic finding indicating that 5 percent or more of the nucleated cells in a bone marrow sample are immature mononuclear cells of lymphoid origin.]
C-SSRS Already Enrolled Subjects - Deterrents to Most Severe Ideation (Since Study Start)	NCIT_C107053	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) Are there things-anyone or anything (e.g., family, religion, pain of death) that stopped you from wanting to die or acting on thoughts of committing suicide? (Since Study Start).]
CF1 Mouse	NCIT_C15003
Lymphoblasts 20 Percent or More of Peripheral Blood White Cells	NCIT_C146662	[A semi-quantitative microscopic finding indicating that 20 percent or more of the nucleated cells in a peripheral leukocyte sample are immature mononuclear cells of lymphoid origin.]
Blasts 20 Percent or More of Peripheral Blood White Cells	NCIT_C36213	[A semi-quantitative microscopic finding indicating that 20 percent or more of the nucleated cells in a peripheral leukocyte sample are immature mononuclear cells.]
Atypical Lymphocytes Present in Peripheral Blood	NCIT_C36249	[A variation of lymphocytes found in a peripheral blood smear that are larger, with abundant cytoplasm, and having nuclei with multiple nucleoli.]
C-SSRS Already Enrolled Subjects - Reasons For Most Severe Ideation (Prior to Study Entry)	NCIT_C107054	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) What sort of reasons did you have for thinking about wanting to die or killing yourself? Was it to end the pain or stop the way you were feeling (in other words you couldn't go on living with this pain or how you were feeling) or was it to get attention, revenge or a reaction from others? Or both? (Prior to Study Entry).]
CF0 Mouse	NCIT_C15004
Pleuritic Pain, CTCAE 5.0	NCIT_C146663	[A disorder characterized by a sensation of marked discomfort in the pleura.]
C-SSRS Already Enrolled Subjects - Reasons For Most Severe Ideation (Since Study Start)	NCIT_C107055	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) What sort of reasons did you have for thinking about wanting to die or killing yourself? Was it to end the pain or stop the way you were feeling (in other words you couldn't go on living with this pain or how you were feeling) or was it to get attention, revenge or a reaction from others? Or both? (Since Study Start).]
Unknown Origin, Rockland USA	NCIT_C15005
Prostatic Pain, CTCAE 5.0	NCIT_C146664	[A disorder characterized by a sensation of marked discomfort in the prostate gland.]
C-SSRS Already Enrolled Subjects - Actual Suicide Attempt (Prior to Study Entry)	NCIT_C107056	[Columbia-Suicidality Severity Rating Scale Already Enrolled Subjects (C-SSRS Already Enrolled Subjects ) Have you made a suicide attempt? Have you done anything to harm yourself? Have you done anything dangerous where you could have died? (Prior to Study Entry).]
RAP/Ko Mouse	NCIT_C15006