Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Abnormal Hematology Test Result	NCIT_C35877	[A laboratory test result that indicates the presence of abnormal peripheral blood and/or bone marrow values.]
K ATP Associated Transient Neonatal Diabetes Mellitus	NCIT_C131846	[K ATP channel-associated neonatal diabetes mellitus that resolves spontaneously.]
Blast Cells Present in Peripheral Blood	NCIT_C35881
Colorectal Cancer pT3 TNM Finding v6	NCIT_C60846	[Colorectal cancer with invasion through the muscularis propria into the submucosa, or into non-peritonealized pericolic or perirectal soft tissues. (from AJCC 6th Ed.)]
PSMD10 Gene	NCIT_C21239	[This gene is involved in protein degradation.]
Regulatory Gene	NCIT_C20194	[Regulatory Genes encode products that regulate or circumscribe the activity of diverse cellular functions.]
Ubiquitinated Protein Degradation	NCIT_C21243	[Ubiquitinated Protein Degradation involves the regulated covalent conjugation of one or more ubiquitin residues to one or more sites on a protein that acts as a tag by which the protein-transport machinery ferries the targeted ubiquinated protein to the proteasome for proteolytic destruction.]
Polyubiquitination	NCIT_C21587	[The type of ubiquitin modification determines the functional consequences for the modified protein. Polyubiquitination, which involves chains of usually four or more ubiquitins, typically seen on cytoplasmic proteins, serve as an efficient signal for recognition by the proteasome and subsequent protein degradation. (From PMID and NCI)]
Colorectal Cancer pT3 a/b TNM Finding	NCIT_C60847	[Colorectal cancer with invasion through the muscularis propria into the submucosa, or into non-peritonealized pericolic or perirectal soft tissues, with tumor extension of 5 mm or less beyond the border of the muscularis propria. (from CAP Colorectal Cancer Protocol-January 2005 Revision)]
Colorectal Cancer pT3 c/d TNM Finding	NCIT_C60848	[Colorectal cancer with invasion through the muscularis propria into the submucosa, or into non-peritonealized pericolic or perirectal soft tissues, with tumor extension of more than 5 mm beyond the border of the muscularis propria. (from CAP Colorectal Cancer Protocol-January 2005 Revision)]
Colorectal Cancer pT4 TNM Finding v6	NCIT_C60849	[Colorectal cancer with direct invasion of adjacent organs or structures and/or perforation of the visceral peritoneum. Direct invasion in T4 includes invasion of other segments of the colorectum by way of the serosa. Invasion of the sigmoid colon by a carcinoma of the cecum, for example, should be classified as T4. Tumor that is adherent to other organs or structures macroscopically is classified as T4. However, if on microscopic examination, no tumor is present in the adhesion, the classification should be pT3. V and L substaging should be used to indicate the presence or absence of vascular or lymphatic invasion. (from AJCC 6th Ed.)]
CKB Gene	NCIT_C21234	[This gene plays a role in cellular energy homeostasis.]
Kinase Family Gene	NCIT_C25872	[Kinase Family Genes encode Kinase enzymes that covalently transfer the terminal, gamma phosphate group from ATP to a variety of substrates and typically play key regulatory roles in diverse cellular functions.]
Phosphorylation Process	NCIT_C16983	[The creation of a phosphate derivative of an organic molecule. This is usually achieved by transferring a phosphate group from ATP via the action of a kinase.]
Homeostatic Process	NCIT_C25989	[The body's maintenance of a consistent internal environment within a narrow range of variation. It is important to the continuation of life.]
Energy Metabolism Process	NCIT_C16547	[Any subcellular or molecular event, process, or condition concerned with storing and generating metabolic energy.]
Colorectal Cancer pTis Intraepithelial TNM Finding	NCIT_C60842	[Colorectal cancer in situ in which cancer cells are confined within the glandular basement membrane (intraepithelial). (from CAP Colorectal Cancer Protocol-January 2005 Revision)]
TNKS Gene	NCIT_C21235	[This gene is involved in telomere maintenance and protein-protein interaction mediation.]
Telomere Maintenance Gene	NCIT_C20338	[Telomere Maintenance Genes encode specialized proteins bound to telomeric DNA repeats and directly involved in maintaining/protecting chromosome telomere ends to prevent a damage response that halts cell proliferation. Telomerase, which lengthens telomeric DNA by RNA-templated addition of repeated DNA sequences, is regulated by proteins that bind to the telomeric DNA repeats and to additional proteins to assemble a higher-order telomeric complex. (NCI)]
Spindle Assembly Interaction	NCIT_C40545	[Spindle Assembly Interaction involves temporary non-covalent binding through intermolecular physical forces of attraction with the mitotic spindle that can affect spindle function and mitosis.]