Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Colorectal Cancer pTis Lamina Propria Invasion TNM Finding	NCIT_C60843	[Colorectal cancer in situ involving the lamina propria (intramucosal) without extension through the muscularis mucosa into the submucosa. (from CAP Colorectal Cancer Protocol-January 2005 Revision)]
TYRP1 Gene	NCIT_C21236	[This gene plays a role in melanogenesis and sensory transduction/vision.]
Oxidoreductase Gene	NCIT_C25939	[Oxidoreductase Genes encode the class of enzymes that catalyze oxidation/reduction reactions (Oxidoreductases). The oxidized substrate is regarded as a hydrogen donor. Systematic enzyme names employ dehydrogenase wherever possible, or reductase; oxidase is only used where O2 is the acceptor.]
Oxidation/Reduction	NCIT_C16945	[All electron-transfer reactions are considered oxidation/reduction reactions. The substance gaining electrons ("oxidizing agent" or "oxidant") is oxidizing the substance that is losing electrons ("reducing agent" or "reductant"). In the process, the "oxidizing agent" is itself reduced by the "reducing agent."]
Colorectal Cancer pT1 TNM Finding v6 and v7	NCIT_C60844	[Colorectal cancer with invasion into the submucosa. (from AJCC 6th and 7th Eds.)]
Tumor Susceptibility Gene 101 Protein	NCIT_C21237	[Tumor susceptibility gene 101 protein (390 aa, ~44 kDa) is encoded by the human TSG101 gene. This protein is involved in both the binding and transport of ubiquitinated proteins.]
Regulatory Protein	NCIT_C18466	[Encoded by Regulatory Genes, Regulatory Proteins regulate or circumscribe the activity of many cellular functions.]
Colorectal Cancer pT2 TNM Finding v6 and v7	NCIT_C60845	[Colorectal cancer with invasion into the muscularis propria. (from AJCC 6th and 7th Eds.)]
Replication Process	NCIT_C21241
Vacuolar Protein Sorting	NCIT_C21242	[Vacuolar Protein Sorting consists of subcellular and biochemical mechanisms involving cell membranes that govern the subcellular location of certain membrane-bound or -associated proteins.]
Membrane Protein Traffic	NCIT_C19429	[Posttranslational modification of proteins targeted for membranes.]
Vacuole	NCIT_C13284	[Any membrane-enclosed spaces or cavities within a cell.]
Protein Degradation Process	NCIT_C18104	[Specific degradation of a protein - involving conjugation, transport, oxidation, and proteolysis - involved in signal transduction or cell communication events; not to be confuse with proteolysis, which applies only to peptide bond hydrolysis. (NCI)]
HIV Budding	NCIT_C21244	[HIV Budding is a process in which newly generated viral RNA and protein complexes are assembled at, packaged in, and released from the cell surface membrane taking a piece of the cell membrane to form their own viral membranes. To bud from infected cells, HIV-1 employs several host proteins such as endosomal sorting protein Tsg101, which functions in the Vps pathway. The L domain (PTAP) in the p6 domain of HIV-1 Gag interacts with the N-terminal domain of TSG101; the Vps28-binding domain of TSG101 inhibits budding.]
Virus-Cell Membrane Interaction	NCIT_C19356	[A function, activity, or process involving the physical interaction between a virus or viral particle and a cell membrane.]
Translation Process Gene	NCIT_C21240	[Genes that encode products which participate in translation, a complex mechanism that occurs on ribosomes. During this process, a peptide or protein is synthesized by utilizing an mRNA transcript to specify the sequence of amino acids in the resulting polypeptide. There are numerous translation process genes, as the synthesis of polypeptides requires ribosomal RNA, transfer RNA, GTP and proteins involved specifically in the activation of amino acids, initiation of synthesis, elongation and termination of synthesis.]
Gene	NCIT_C16612	[A functional unit of heredity which occupies a specific position on a particular chromosome and serves as the template for a product that contributes to a phenotype or a biological function.]
Translation Process	NCIT_C30022	[A Translation Process consists of enzymatic reactions by which polypeptides are synthesized on ribosomes from information in mRNA transcripts to specify the sequence of amino acids in the polypeptide chain.]
Insulin Resistant Diabetes Mellitus with Acanthosis Nigricans and Hyperandrogenism	NCIT_C131836	[A syndrome of insulin resistance caused by mutation(s) in the INSR gene, encoding the insulin receptor. This condition is characterized by a clinical triad of hyperinsulinemia, acanthosis nigricans, and hyperandrogenism without lipodystrophy. This is the least severe of a spectrum of disorders; the other two conditions are Rabson-Mendenhall Syndrome and Donohoe Syndrome.]
Anisochromasia	NCIT_C35879