Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
ATR Gene	NCIT_C20560	[This gene is involved in cell cycle checkpoints and DNA recombination.]
TREX2 Gene	NCIT_C20561	[This gene is involved in DNA repair and in the maintenance of DNA integrity.]
TERF2 Gene	NCIT_C20562	[This gene is involved in the negative regulation of telomerase activity.]
Gastric Carcinoma	NCIT_C4911	[A malignant epithelial tumor of the stomach mucosa. The vast majority of gastric carcinomas are adenocarcinomas, arising from the gastric glandular epithelium.]
Telomere Length Maintenance	NCIT_C20336	[Telomeres in human cancer cells consist of a tandem array of telomeric DNA repeats bound to a specialized telomeric proteins. Telomeres allow cells to distinguish natural chromosome ends from damaged DNA. When telomere function is disrupted, a potentially lethal DNA damage response can ensue, DNA repair activities threaten the integrity of chromosome ends, and extensive genome instability can arise. Both telomerase and recombination can lengthen telomeres. (from PMID 11850780 and NCI)]
Dietary Gum	NCIT_C68500
Dietary Polysaccharide	NCIT_C70550
Dietary Fiber	NCIT_C68492
Thromboxane B2	NCIT_C107560	[An eicosanoid and biologically inactive metabolite of thromboxane A2. Thromboxane B2 is released during anaphylaxis. As thromboxane A2 has a short half-life, the levels of thromboxane B2 can be used to indirectly measure the production of thromboxane A2]
Thromboxane	NCIT_C879	[Any eicosanoid with a 6-membered ether-containing ring with potential prothrombotic activity. Thromboxanes are synthesized from prostaglandin H2 by thromboxane-A synthase in activated platelets.]
Certain	NCIT_C107561	[Having no doubts; definitely true.]
Angiotensin-2	NCIT_C107562	[Angiotensin-2 (8 aa, ~1 kDa) is encoded by the human AGT gene. This protein is involved in vasoconstriction, heart rate and renal absorption of water and sodium.]
AGT Gene Product	NCIT_C136722	[A protein encoded by the human AGT gene.]
Fibrin Monomer	NCIT_C107563	[Derivatives of thrombin-cleaved fibrinogen that are plasma soluble due to limiting amounts of the clot promoting protein factor XIII. Detection of these proteins may be used to aid in the diagnosis or exclusion of thrombotic events or determine if a patient is at risk for post-operative hemorrhage.]
S-Nitroso-Hemoglobin	NCIT_C107564	[Hemoglobin that has a nitric oxide bound to the cysteine at position 93 in the beta-globin chain.]
FGFR2 NM_000141.4:c.1647T>A	NCIT_C107598	[A nucleotide substitution at position 1647 of the coding sequence of the FGFR2 gene where thymine has been mutated to adenine.]
FGFR2 NP_000132.3:p.N549K	NCIT_C107600	[A change in the amino acid residue at position 549 in the fibroblast growth factor receptor 2 protein where asparagine has been replaced by lysine.]
Upper Jugular Lymph Node Group (Sublevels IIA and IIB)	NCIT_C132510	[Lymph nodes located around the upper third of the internal jugular vein and adjacent spinal accessory nerve, extending from the level of the skull base (above) to the level of the inferior border of the hyoid bone (below). The anterior (medial) boundary is the stylohyoid muscle (the radiologic correlate is the vertical plane defined by the posterior surface of the submandibular gland) and the posterior (lateral) boundary is the posterior border of the sternocleidomastoid muscle. Sublevel IIA nodes are located anterior (medial) to the vertical plain defined by the spinal accessory nerve. Sublevel IIB nodes are located posterior (lateral) to the vertical plane defined by the spinal accessory nerve (the radiologic correlate is the lateral border of the internal jugular on a contrast-enhanced CT scan). The upper jugular nodes are at greatest risk for harboring metastases from cancers arising from the oral cavity, nasal cavity, nasopharynx, oropharynx, hypopharynx, larynx, and parotid gland. (AJCC 8th ed.)]
Neck Lymph Node Groups	NCIT_C132507	[Lymph node groups found within the seven levels and sublevels of the neck. (AJCC 8th ed.)]
FGFR2 NM_000141.4:c.1647T>G	NCIT_C107599	[A nucleotide substitution at position 1647 of the coding sequence of the FGFR2 gene where thymine has been mutated to guanine.]