Terminology Service < Semantic Lookup Platform

All terms in ONE

Label	Id	Description
laser scanning confocal microscope	OBI_0001125	[A confocal microscope that obtains high-resolution optical images with depth selectivity, in which a laser beam passes through a light source aperture and then is focused by an objective lens into a small (ideally diffraction limited) focal volume within or on the surface of a specimen.]
precision nuclear run-on sequencing assay	OBI_0002457	[An RNA-seq assay that maps the genome-wide distribution of transcriptionally-engaged Pol II at base-pair resolution by using biotin-labeled ribonucleotide triphosphate analogs (biotin-NTP) for nuclear run-on reactions, allowing the efficient affinity purification of nascent RNAs for high throughput sequencing from their 3' ends.]
digital microscope	OBI_0001126	[A microscope that uses optics and a charge-coupled device (CCD) camera to output a digital image to a monitor.]
chromosome conformation capture-on-chip assay	OBI_0002458	[A nuclear ligation assay which uses cross-linking of proteins to proteins and DNA, followed by two rounds of digestion and ligation, inverse PCR, and characterization by microarray or DNA sequencing. This enables unbiased genome-wide screens for DNA contacts made by single genomic sites of interest.]
inverse polymerase chain reaction	OBI_0002598	[A polymerase chain reaction which amplifies DNA with only one known sequence from which primers may be designed. A series of restriction digestions and ligations result in a looped DNA fragment which can be primed for PCR.]
freeze substitution system	OBI_0001127	[A device or system for dehydrating and then chemically fixing electron microscopy samples at low temperatures in preparation for various treatments including embedding in resins.]
genotype phasing by Hi-C assay	OBI_0002459	[A genotyping assay in which carbon-copy chromosome conformation is used to detect polymorphism in DNA samples.]
Hi-C assay	OBI_0002440	[A chromosome conformation capture assay that detects genome-wide chromosomal interactions. High-throughput techniques are used to sequence the ligated fragments after cross-linking and cutting with restriction enzymes.]
micropipette	OBI_0001128	[A microinjection device that is used to measure very small volumes of liquids.]
voltage clamp device	OBI_0001129	[A device that is used to measure the ion currents across the membrane of excitable cells, such as neurons, while holding the membrane voltage at a set level.]
hydroxyl-radical footprinting assay measuring binding of a B cell epitope:antibody complex	OBI_0002450	[A footprinting assay that uses hydroxyl-radical footprinting to measure B cell epitope qualitative binding to antibody.]
ELISA measuring epitope specific interferon-alpha production by T cells	OBI_0002451	[An assay of epitope specific interferon-alpha production by T cells that uses an ELISA.]
biological activity assay measuring epitope specific interferon-alpha production by T cells	OBI_0002452	[A T cell epitope specific cytokine production assay that detects interferon-alpha production by T cells.]
portable fluorometer	OBI_0001120	[A compact fluorometer that can be carried or moved with ease.]
gel electrophoresis system	OBI_0001121	[A device that moves charged particles through a medium by using an electric field induced by electrodes.]
health status inclusion criterion	OBI_0002453	[An inclusion criterion that defines and states one or more clinically significant bodily components, dispositions, and/or bodily processes of an entity that are inferred from relevant clinical findings or self-reported, which, if met, makes the entity suitable for a given task or participation in a given process.]
diffractometer	OBI_0001122	[A measurement device for analyzing the structure of a material from the scattering pattern produced when a beam of radiation or particles (e.g. X rays or neutrons) interacts with it.]
obsolescence reason specification	IAO_0000225	[The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.]
cellular response to DNA damage stimulus	GO_0006974	[Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.]
age since culture seeding measurement datum	OBI_0002465	[An age measurement datum that is the result of the measurement of the age of a cell since cultured (the process of seeding cells onto a culture dish).]