Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
LOC102554639	rgd:7561514
Atp1b1	rgd:2170	[ENCODES a protein that exhibits protein heterodimerization activity; sodium:potassium-exchanging ATPase activity; ATP binding (ortholog); INVOLVED IN metal ion transport; potassium ion transport; response to hypoxia; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH sensorineural hearing loss; 1q24 Deletion Syndrome (ortholog); acute myeloid leukemia (ortholog); FOUND IN apical plasma membrane; basolateral plasma membrane; caveola; INTERACTS WITH 1-(5-isoquinolinesulfonyl)-2-methylpiperazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine]
Atp1b2	rgd:2171	[ENCODES a protein that exhibits protein heterodimerization activity; sodium:potassium-exchanging ATPase activity; ATPase activator activity (ortholog); INVOLVED IN cellular potassium ion homeostasis (ortholog); cellular sodium ion homeostasis (ortholog); membrane repolarization (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH malignant glioma (ortholog); FOUND IN apical plasma membrane; cell periphery; membrane; INTERACTS WITH 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil; acrylamide]
Tas2r106	rgd:2314260	[ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred)]
Atp1b3	rgd:2172	[ENCODES a protein that exhibits sodium:potassium-exchanging ATPase activity; ATPase activator activity (ortholog); ATPase binding (ortholog); INVOLVED IN metal ion transport; potassium ion transport; sodium ion transport; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; FOUND IN caveola; plasma membrane; sodium:potassium-exchanging ATPase complex; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine]
LOC102556630	rgd:7693396
Fxyd2	rgd:2173	[ENCODES a protein that exhibits sodium channel regulator activity (ortholog); INVOLVED IN cellular hyperosmotic salinity response; monovalent inorganic cation transport; negative regulation of cell population proliferation; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); hypertension (ortholog); primary hypomagnesemia (ortholog); FOUND IN basolateral plasma membrane; intracellular membrane-bounded organelle; plasma membrane; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine]
Atp2a2	rgd:2174	[ENCODES a protein that exhibits ATP binding; calcium ion binding; calcium transmembrane transporter activity, phosphorylative mechanism; INVOLVED IN calcium ion import into sarcoplasmic reticulum; calcium ion transmembrane transport; calcium ion transport; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1; Cachexia; Cardiomegaly; FOUND IN apical ectoplasmic specialization; extrinsic component of cytoplasmic side of plasma membrane; perinuclear region of cytoplasm; INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine]
LOC103694859	rgd:9383390
Atp2a3	rgd:2175	[ENCODES a protein that exhibits calcium ion transmembrane transporter activity; calcium transmembrane transporter activity, phosphorylative mechanism; calcium-dependent ATPase activity; INVOLVED IN calcium ion transmembrane transport; endoplasmic reticulum calcium ion homeostasis; liver regeneration; PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; Alzheimer's disease pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; hypertension; adenoma (ortholog); FOUND IN endoplasmic reticulum (ortholog); organelle membrane (ortholog); sarcoplasmic reticulum (ortholog); INTERACTS WITH 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil; ammonium chloride]
Atp2b2	rgd:2176	[ENCODES a protein that exhibits ATP binding; calcium transmembrane transporter activity, phosphorylative mechanism; glutamate receptor binding; INVOLVED IN brain development; neural retina development; auditory receptor cell stereocilium organization (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness 12 (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN apical plasma membrane; dendrite; GABA-ergic synapse; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 17alpha-ethynylestradiol]
LOC102550588	rgd:7742898
Atp4a	rgd:2177	[ENCODES a protein that exhibits potassium:proton exchanging ATPase activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN pH reduction (ortholog); regulation of proton transport (ortholog); response to drug (ortholog); PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; esomeprazole pharmacokinetics pathway; FOUND IN apical plasma membrane; plasma membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; ammonium chloride]
Atp4b	rgd:2178	[ENCODES a protein that exhibits drug binding; INVOLVED IN pH reduction; response to lipopolysaccharide; response to organonitrogen compound; PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; esomeprazole pharmacokinetics pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; obesity; atrophic gastritis (ortholog); FOUND IN membrane; INTERACTS WITH ammonium chloride; bisphenol A; copper atom]
Atp7a	rgd:2179	[ENCODES a protein that exhibits chaperone binding; Rac GTPase binding; copper ion binding (ortholog); INVOLVED IN cellular response to amino acid stimulus; cellular response to antibiotic; cellular response to cadmium ion; PARTICIPATES IN cisplatin drug pathway; ASSOCIATED WITH Alzheimer's disease; congenital diaphragmatic hernia; Diabetic Cardiomyopathies; FOUND IN apical plasma membrane; basolateral plasma membrane; brush border membrane; INTERACTS WITH 1,2-dimethylhydrazine; 2,2,2-tetramine; 6-propyl-2-thiouracil]
Crhr2	rgd:70547	[ENCODES a protein that exhibits corticotropin-releasing hormone receptor activity; peptide hormone binding; corticotrophin-releasing factor receptor activity (ortholog); INVOLVED IN actin filament organization; catecholamine biosynthetic process; cellular response to glucocorticoid stimulus; PARTICIPATES IN protein kinase A (PKA) signaling pathway; corticotropin-releasing hormone signaling pathway; G protein mediated signaling pathway via Galphas family; ASSOCIATED WITH Anorexia; colitis; Fetal Hypoxia; FOUND IN axon; axon terminus; cell body fiber; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; ammonium chloride]
Ppbp	rgd:70548	[ENCODES a protein that exhibits chemokine activity (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); killing of cells of other organism (ortholog); leukocyte migration involved in inflammatory response (ortholog); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH allergic hypersensitivity disease (ortholog); hypertension (ortholog); Lung Neoplasms (ortholog); FOUND IN platelet alpha granule (ortholog); INTERACTS WITH acrylamide; ammonium chloride; amphetamine]
Hrk	rgd:70549	[INVOLVED IN apoptotic process; cellular response to potassium ion starvation; positive regulation of neuron apoptotic process; PARTICIPATES IN intrinsic apoptotic pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH (+)-pilocarpine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine]
LOC102551705	rgd:7693387
Baat	rgd:2190	[ENCODES a protein that exhibits glycine N-choloyltransferase activity; long-chain acyl-CoA hydrolase activity (ortholog); medium-chain acyl-CoA hydrolase activity (ortholog); INVOLVED IN animal organ regeneration; bile acid conjugation; liver development; PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; ASSOCIATED WITH Sepsis; atypical hemolytic-uremic syndrome (ortholog); disease of metabolism (ortholog); FOUND IN cytosol; peroxisome; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol]