Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
Atp7b	rgd:2180	[ENCODES a protein that exhibits copper ion binding; copper ion transmembrane transporter activity; zinc ion binding; INVOLVED IN cellular response to copper ion; cellular response to manganese ion; circadian rhythm; PARTICIPATES IN cisplatin drug pathway; ASSOCIATED WITH Wilson disease; Acute Liver Failure (ortholog); Animal Disease Models (ortholog); FOUND IN apical part of cell; basolateral plasma membrane; bicellular tight junction; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene]
Atp5if1	rgd:2181	[ENCODES a protein that exhibits ATPase inhibitor activity; angiostatin binding (ortholog); ATPase binding (ortholog); INVOLVED IN erythrocyte differentiation (ortholog); heme biosynthetic process (ortholog); mitochondrial depolarization (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); fatty liver disease (ortholog); FOUND IN mitochondrion; cell surface (ortholog); protein-containing complex (ortholog); INTERACTS WITH 2,4,6-trinitrotoluene; 2,4-dinitrotoluene; 2,6-dinitrotoluene]
LOC102553787	rgd:7693380
Avp	rgd:2184	[ENCODES a protein that exhibits neuropeptide hormone activity; V1A vasopressin receptor binding; V1B vasopressin receptor binding; INVOLVED IN grooming behavior; hyperosmotic salinity response; locomotory behavior; PARTICIPATES IN vasopressin signaling pathway; vasopressin signaling pathway via receptor type 1; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH Dehydration; Febrile Seizures; hyperglycemia; FOUND IN dendrite; extracellular space; secretory granule; INTERACTS WITH (R)-noradrenaline; (S)-colchicine; (S)-nicotine]
Avpr1a	rgd:2185	[ENCODES a protein that exhibits peptide hormone binding; V1A vasopressin receptor binding; vasopressin receptor activity; INVOLVED IN calcium-mediated signaling; cellular response to water deprivation; grooming behavior; PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; vasopressin signaling pathway; vasopressin signaling pathway via receptor type 1; ASSOCIATED WITH acute kidney failure; brain edema; Brain Injuries; FOUND IN cytoplasmic vesicle; plasma membrane; endocytic vesicle (ortholog); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine]
Avpr2	rgd:2186	[ENCODES a protein that exhibits vasopressin receptor activity (ortholog); INVOLVED IN negative regulation of renal sodium excretion; negative regulation of urine volume; positive regulation of blood pressure; PARTICIPATES IN vasopressin signaling pathway; vasopressin signaling pathway via receptor type 2; G protein mediated signaling pathway via Galphas family; ASSOCIATED WITH hypertension; ureteral obstruction; adrenoleukodystrophy (ortholog); FOUND IN endocytic vesicle (ortholog); endosome (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bis(2-ethylhexyl) phthalate]
Azgp1	rgd:2187	[INVOLVED IN cell adhesion (ortholog); detection of chemical stimulus involved in sensory perception of bitter taste (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); Lung Neoplasms (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN extracellular space (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride]
B2m	rgd:2189	[ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN response to cadmium ion; response to drug; amyloid fibril formation (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; antigen processing and presentation pathway; ASSOCIATED WITH acute kidney failure; Experimental Liver Cirrhosis; pyelonephritis; FOUND IN extracellular space; cytosol (ortholog); external side of plasma membrane (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine]
LOC108350096	rgd:11489382
LOC102549488	rgd:7742870
LOC102554988	rgd:7727235
Bace1	rgd:2191	[ENCODES a protein that exhibits peptidase activity; amyloid-beta binding (ortholog); aspartic-type endopeptidase activity (ortholog); INVOLVED IN amyloid-beta metabolic process; cellular response to amyloid-beta; cellular response to copper ion; PARTICIPATES IN Alzheimer's disease pathway; ASSOCIATED WITH abnormal motor coordination/balance; decreased myelin sheath thickness; decreased startle reflex; ASSOCIATED WITH Alzheimer's disease; Chronic Cerebral Hypoperfusion; Cognitive Dysfunction; FOUND IN axon; dendrite; endosome; INTERACTS WITH 17alpha-ethynylestradiol; 6-propyl-2-thiouracil; acrolein]
Bax	rgd:2192	[ENCODES a protein that exhibits BH domain binding; chaperone binding; heat shock protein binding; INVOLVED IN aging; apoptotic process; brain development; PARTICIPATES IN intrinsic apoptotic pathway; ceramide signaling pathway; syndecan signaling pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1; acute kidney failure; Acute Lung Injury; FOUND IN cytoplasm; cytosol; mitochondrial membrane; INTERACTS WITH (+)-alpha-tocopherol; (+)-catechin; (+)-pilocarpine]
Bc1	rgd:2193	[INVOLVED IN regulation of translational initiation]
Bcan	rgd:2194	[ENCODES a protein that exhibits calcium ion binding (inferred); carbohydrate binding (inferred); hyaluronic acid binding (inferred); INVOLVED IN brain development; cell-matrix adhesion; gliogenesis; ASSOCIATED WITH Hypoxia-Ischemia, Brain; malignant glioma; middle cerebral artery infarction; FOUND IN anchored component of membrane; axon; axon initial segment; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acrylamide]
Bcat1	rgd:2195	[ENCODES a protein that exhibits branched-chain-amino-acid transaminase activity; identical protein binding; INVOLVED IN branched-chain amino acid catabolic process (ortholog); PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH Brain Injuries; cholestasis (ortholog); Weight Gain (ortholog); FOUND IN cytoplasm; cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil]
Bckdha	rgd:2196	[ENCODES a protein that exhibits protein-containing complex binding; alpha-ketoacid dehydrogenase activity (ortholog); INVOLVED IN response to cAMP; response to glucocorticoid; response to nutrient; PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; maple syrup urine disease (ortholog); Maple Syrup Urine Disease, Type 1A (ortholog); FOUND IN mitochondrial alpha-ketoglutarate dehydrogenase complex (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate]
Bckdhb	rgd:2197	[ENCODES a protein that exhibits protein-containing complex binding; alpha-ketoacid dehydrogenase activity (ortholog); INVOLVED IN response to cAMP; response to glucocorticoid; response to nutrient; PARTICIPATES IN 3-hydroxy-3-methylglutaryl-CoA lyase deficiency pathway; 3-hydroxyisobutyric aciduria pathway; 3-methylcrotonyl CoA carboxylase 1 deficiency pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; lung cancer (ortholog); maple syrup urine disease (ortholog); FOUND IN mitochondrial alpha-ketoglutarate dehydrogenase complex (ortholog); mitochondrion (ortholog); nucleolus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; ammonium chloride]
Bckdk	rgd:2198	[ENCODES a protein that exhibits [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity; ATP binding; protein serine/threonine kinase activity; INVOLVED IN branched-chain amino acid catabolic process; phosphorylation; ASSOCIATED WITH autism spectrum disorder (ortholog); branched-chain keto acid dehydrogenase kinase deficiency (ortholog); FOUND IN mitochondrial alpha-ketoglutarate dehydrogenase complex; mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; clofibric acid]
Bcl2	rgd:2199	[ENCODES a protein that exhibits BH domain binding; protein-containing complex binding; BH3 domain binding (ortholog); INVOLVED IN aging; apoptotic process; brain development; PARTICIPATES IN intrinsic apoptotic pathway; ceramide signaling pathway; erythropoietin signaling pathway; ASSOCIATED WITH abdominal obesity-metabolic syndrome 1; acute kidney failure; Acute Lung Injury; FOUND IN cytoplasm; cytosol; mitochondrial crista; INTERACTS WITH (+)-alpha-tocopherol; (+)-catechin; (+)-pilocarpine]