Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
Samm50	rgd:1303219	[INVOLVED IN cristae formation (ortholog); mitochondrial respiratory chain complex assembly (ortholog); protein insertion into mitochondrial outer membrane (ortholog); PARTICIPATES IN beta-barrel pathway of mitochondrial protein import; ASSOCIATED WITH non-alcoholic fatty liver disease (ortholog); FOUND IN integral component of membrane (ortholog); mitochondrial outer membrane (ortholog); mitochondrion (ortholog); INTERACTS WITH 2,4,6-trinitrotoluene; 2,6-dinitrotoluene; atrazine]
LOC108352519	rgd:11465431
Camk2a	rgd:2261	[ENCODES a protein that exhibits calmodulin-dependent protein kinase activity; GTPase activating protein binding; calcium-dependent protein serine/threonine kinase activity (ortholog); INVOLVED IN calmodulin dependent kinase signaling pathway; ionotropic glutamate receptor signaling pathway; NMDA selective glutamate receptor signaling pathway; PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; fibroblast growth factor signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Hearing Loss, Cisplatin-Induced; Hyperalgesia; Inflammation; FOUND IN axon; cytosol; dendrite; INTERACTS WITH 17beta-estradiol; 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile; 6-propyl-2-thiouracil]
U6	rgd:15013851
Camk2b	rgd:2262	[ENCODES a protein that exhibits calmodulin-dependent protein kinase activity; phospholipase binding; protein kinase binding; INVOLVED IN cell projection morphogenesis; cellular response to homocysteine; hippocampal neuron apoptotic process; PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; p38 MAPK signaling pathway; type II interferon signaling pathway; ASSOCIATED WITH Hearing Loss, Cisplatin-Induced; autosomal dominant mental retardation 54 (ortholog); cannabis abuse (ortholog); FOUND IN dendrite; glutamatergic synapse; perikaryon; INTERACTS WITH (S)-amphetamine; 2,4,6-trinitrobenzenesulfonic acid; 4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol]
Camk2d	rgd:2263	[ENCODES a protein that exhibits calmodulin-dependent protein kinase activity; ion channel binding; nitric-oxide synthase binding; INVOLVED IN cardiac muscle cell contraction; cell growth involved in cardiac muscle cell development; cellular potassium ion homeostasis; PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; type II interferon signaling pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH seizures; ASSOCIATED WITH epilepsy; aniridia (ortholog); atrial fibrillation (ortholog); FOUND IN cytoplasm; cytosol; nucleus; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 3H-1,2-dithiole-3-thione]
Camk4	rgd:2264	[ENCODES a protein that exhibits calmodulin-dependent protein kinase activity; INVOLVED IN protein phosphorylation; long-term memory (ortholog); myeloid dendritic cell differentiation (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; long term potentiation; neurotrophic factor signaling pathway; ASSOCIATED WITH Cocaine-Related Disorders (ortholog); Hereditary Neoplastic Syndromes (ortholog); intellectual disability (ortholog); FOUND IN glutamatergic synapse; postsynapse; cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile]
Calm-ps1	rgd:2265	[processed calmodulin pseudogene]
Canx	rgd:2266	[ENCODES a protein that exhibits apolipoprotein binding; ionotropic glutamate receptor binding; INVOLVED IN aging; clathrin-dependent endocytosis (ortholog); synaptic vesicle endocytosis (ortholog); PARTICIPATES IN antigen processing and presentation pathway; Endoplasmic Reticulum-associated degradation pathway; phagocytosis pathway; ASSOCIATED WITH Chemical and Drug Induced Liver Injury (ortholog); Myocardial Ischemia (ortholog); obesity (ortholog); FOUND IN axon; cytoplasm; dendrite cytoplasm; INTERACTS WITH (+)-alpha-tocopherol; 2,4-dinitrotoluene; 3H-1,2-dithiole-3-thione]
Capn1	rgd:2267	[ENCODES a protein that exhibits calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoskeletal protein binding; INVOLVED IN aging; brain development; cellular response to hydrogen peroxide; PARTICIPATES IN the proteolytic pathway involving calcium-dependent proteases; Alzheimer's disease pathway; apoptotic cell death pathway; ASSOCIATED WITH acute kidney failure; aortic atherosclerosis; Brain Injuries, Traumatic; FOUND IN cytosol; membrane; mitochondrion; INTERACTS WITH (S)-colchicine; 1,2,4-trimethylbenzene; 2,4,6-trinitrobenzenesulfonic acid]
Farsb	rgd:1303210	[ENCODES a protein that exhibits phenylalanine-tRNA ligase activity (ortholog); INVOLVED IN phenylalanyl-tRNA aminoacylation (ortholog); protein heterotetramerization (ortholog); PARTICIPATES IN phenylketonuria pathway; tyrosinemia type II pathway; tyrosinemia type III pathway; ASSOCIATED WITH Aneurysm (ortholog); Fibrosis (ortholog); INTERSTITIAL LUNG AND LIVER DISEASE (ortholog); FOUND IN phenylalanine-tRNA ligase complex (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene]
LOC108351474	rgd:11465430
Capn2	rgd:2268	[ENCODES a protein that exhibits calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoskeletal protein binding; INVOLVED IN behavioral response to pain; cellular response to amino acid stimulus; cellular response to interferon-beta; PARTICIPATES IN the proteolytic pathway involving calcium-dependent proteases; Alzheimer's disease pathway; apoptotic cell death pathway; ASSOCIATED WITH Anthracycline-induced Cardiotoxicity; Brain Injuries, Traumatic; Hyperalgesia; FOUND IN cell projection; cytoplasm; cytosol; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione]
Aurkaip1	rgd:1303211	[ENCODES a protein that exhibits kinase activity (inferred); INVOLVED IN positive regulation of proteolysis (ortholog); ASSOCIATED WITH Goldberg-Shprintzen syndrome (ortholog); idiopathic generalized epilepsy (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN intracellular membrane-bounded organelle (ortholog); mitochondrion (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; finasteride]
Capn3	rgd:2269	[ENCODES a protein that exhibits calcium-dependent cysteine-type endopeptidase activity; enzyme binding; peptidase activity; INVOLVED IN proteolysis; response to calcium ion; response to drug; ASSOCIATED WITH hepatocellular carcinoma; Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 4 (ortholog); autosomal recessive limb-girdle muscular dystrophy (ortholog); FOUND IN cytoplasm; myofibril; nucleus; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; amphetamine]
Arrb2-ps	rgd:1303212	[pseudogene of arrestin beta 2 located in the major histocompatibility complex; arrestins are thought to participate in desensitization of G-protein-coupled receptors]
Pgap1	rgd:1303213	[ENCODES a protein that exhibits nuclease activity; phosphoric ester hydrolase activity; INVOLVED IN GPI anchor biosynthetic process; myo-inositol transport; anterior/posterior axis specification (ortholog); PARTICIPATES IN glycosylphosphatidylinositol anchor biosynthetic pathway; ASSOCIATED WITH autosomal recessive non-syndromic intellectual disability (ortholog); Cerebral Visual Impairment and Intellectual Disability (ortholog); High Myopia (ortholog); FOUND IN endoplasmic reticulum; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A]
Emc10	rgd:1303214	[INVOLVED IN positive regulation of angiogenesis (ortholog); positive regulation of endothelial cell migration (ortholog); positive regulation of endothelial cell proliferation (ortholog); FOUND IN ER membrane protein complex (ortholog); extracellular region (ortholog); integral component of membrane (ortholog); INTERACTS WITH bisphenol A; flutamide; nefazodone]
Znf235	rgd:7536417	[ASSOCIATED WITH schizophrenia (ortholog); INTERACTS WITH bisphenol A; benzene (ortholog); copper(II) sulfate (ortholog)]
LOC103693761	rgd:9417113