Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
Cubn	rgd:68355	[ENCODES a protein that exhibits cargo receptor activity; drug binding; hemoglobin binding; INVOLVED IN cobalamin catabolic process; cobalamin transport; endocytic hemoglobin import; ASSOCIATED WITH Diabetic Nephropathies; amphetamine abuse (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); FOUND IN apical plasma membrane; brush border membrane; clathrin-coated pit; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil]
Scamp5	rgd:68356	[ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN regulation of synaptic vesicle endocytosis; negative regulation of endocytosis (ortholog); positive regulation of calcium ion-dependent exocytosis (ortholog); ASSOCIATED WITH autistic disorder (ortholog); schizophrenia (ortholog); FOUND IN integral component of synaptic vesicle membrane; synaptic vesicle; Golgi membrane (ortholog); INTERACTS WITH 3,7-dihydropurine-6-thione; ammonium chloride; copper atom]
Pdcd6ip	rgd:68357	[ENCODES a protein that exhibits SH3 domain binding; calcium-dependent protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN actomyosin contractile ring assembly (ortholog); bicellular tight junction assembly (ortholog); maintenance of epithelial cell apical/basal polarity (ortholog); PARTICIPATES IN endocytosis pathway; ASSOCIATED WITH osteoarthritis (ortholog); FOUND IN cytoplasm; actomyosin (ortholog); cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,4-dinitrotoluene; 2,6-dinitrotoluene]
Acan	rgd:68358	[ENCODES a protein that exhibits calcium ion binding; INVOLVED IN cellular response to growth factor stimulus; central nervous system development; chondroblast differentiation; ASSOCIATED WITH Brain Injuries; congestive heart failure; degenerative disc disease; FOUND IN extracellular space; neuron projection; neuronal cell body; INTERACTS WITH (R)-mevalonic acid; (S)-nicotine; 2-amino-2-deoxy-D-glucopyranose]
Pttg1	rgd:68359	[ENCODES a protein that exhibits heat shock protein binding; ribosome binding; cysteine-type endopeptidase inhibitor activity (ortholog); INVOLVED IN negative regulation of cell population proliferation; regulation of cell growth; chromosome segregation (ortholog); PARTICIPATES IN cell cycle pathway, mitotic; ASSOCIATED WITH Pituitary Neoplasms; hepatocellular carcinoma (ortholog); psoriasis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17beta-estradiol 3-benzoate]
Exoc1	rgd:1304939	[INVOLVED IN phosphatidylinositol-mediated signaling (ortholog); positive regulation of protein secretion (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of apical plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 2-methoxyethanol]
Nr5a1	rgd:68350	[ENCODES a protein that exhibits DNA-binding transcription factor activity; double-stranded DNA binding; sequence-specific DNA binding; INVOLVED IN calcineurin-mediated signaling; female gonad development; hormone-mediated signaling pathway; ASSOCIATED WITH gonadal dysgenesis; 46 XX gonadal dysgenesis (ortholog); 46 XY gonadal dysgenesis (ortholog); FOUND IN nucleus; RNA polymerase II transcription factor complex (ortholog); INTERACTS WITH (S)-nicotine; 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine]
Scamp3	rgd:68351	[ENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); INVOLVED IN response to organic substance (ortholog); response to retinoic acid (ortholog); FOUND IN Golgi membrane (ortholog); intracellular membrane-bounded organelle (ortholog); INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; bisphenol A]
Dhodh	rgd:68352	[ENCODES a protein that exhibits dihydroorotate dehydrogenase activity; drug binding; FMN binding; INVOLVED IN 'de novo' pyrimidine nucleobase biosynthetic process; female pregnancy; lactation; PARTICIPATES IN beta-ureidopropionase deficiency pathway; de novo pyrimidine biosynthetic pathway; dihydropyrimidinase deficiency pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; Experimental Arthritis; Experimental Autoimmune Neuritis; FOUND IN mitochondrial inner membrane; neuronal cell body; cytosol (ortholog); INTERACTS WITH 1,4-naphthoquinone; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene]
Nr5a2	rgd:68353	[ENCODES a protein that exhibits double-stranded DNA binding; nuclear receptor activity; chromatin binding (ortholog); INVOLVED IN calcineurin-mediated signaling; bile acid metabolic process (ortholog); cellular response to leukemia inhibitory factor (ortholog); PARTICIPATES IN maturity-onset diabetes of the young pathway; ASSOCIATED WITH anovulation (ortholog); Chemical and Drug Induced Liver Injury (ortholog); Dyslipidemias (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); RNA polymerase II transcription factor complex (ortholog); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 17alpha-ethynylestradiol; 2-methoxyethanol]
Scamp4	rgd:68354	[INVOLVED IN protein transport (inferred); ASSOCIATED WITH Mental Retardation, Autosomal Recessive 36 (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN transport vesicle; INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; cadmium dichloride]
LOC102554652	rgd:7574938
Perm1	rgd:1304931	[INVOLVED IN regulation of transcription, DNA-templated (ortholog); response to muscle activity (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; bisphenol A]
Pdcd11	rgd:1304933	[ENCODES a protein that exhibits transcription factor binding (ortholog); INVOLVED IN mRNA processing (inferred); PARTICIPATES IN ribosome biogenesis pathway; FOUND IN cytosol (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene]
Rpusd1	rgd:1304934	[ENCODES a protein that exhibits RNA binding (inferred); ASSOCIATED WITH prostate cancer (ortholog); tuberous sclerosis 2 (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; 17beta-estradiol (ortholog)]
Plekhh2	rgd:1304935	[ENCODES a protein that exhibits actin binding (ortholog); identical protein binding (ortholog); INVOLVED IN negative regulation of actin filament depolymerization (ortholog); FOUND IN cortical actin cytoskeleton (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 6-propyl-2-thiouracil; bisphenol A]
Mtfr1	rgd:1304936	[INVOLVED IN aerobic respiration (ortholog); mitochondrial fission (ortholog); mitochondrion organization (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione; 4,4'-diaminodiphenylmethane]
Arap3	rgd:1304938	[ENCODES a protein that exhibits phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-3,4-bisphosphate binding (ortholog); INVOLVED IN negative regulation of cell migration (ortholog); negative regulation of Rac protein signal transduction (ortholog); negative regulation of Rho protein signal transduction (ortholog); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH Hereditary Neoplastic Syndromes (ortholog); human immunodeficiency virus infectious disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (ortholog); lamellipodium (ortholog); ruffle (ortholog); INTERACTS WITH 1,3-dinitrobenzene; amphetamine; bisphenol A]
Cnih2	rgd:1304930	[INVOLVED IN localization within membrane; negative regulation of anterograde synaptic vesicle transport; negative regulation of receptor localization to synapse; ASSOCIATED WITH autosomal recessive cutis laxa type IB (ortholog); FOUND IN AMPA glutamate receptor complex; dendritic shaft; glutamatergic synapse; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; bisphenol A]
Grid1	rgd:68366	[ENCODES a protein that exhibits ionotropic glutamate receptor activity (inferred); INVOLVED IN social behavior (ortholog); ASSOCIATED WITH Colorectal Neoplasms (ortholog); Malformations of Cortical Development, Group II (ortholog); prostate cancer (ortholog); FOUND IN postsynaptic membrane; glutamatergic synapse (ortholog); integral component of postsynaptic density membrane (ortholog); INTERACTS WITH acrylamide; aflatoxin B1; bisphenol A]