Terminology Service < Semantic Lookup Platform

All terms in RGD

Label	Id	Description
LOC102552060	rgd:7741692
Pts	rgd:68367	[ENCODES a protein that exhibits 6-pyruvoyltetrahydropterin synthase activity; identical protein binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN tetrahydrobiopterin biosynthetic process (ortholog); PARTICIPATES IN dopa responsive dystonia pathway; Segawa syndrome pathway; folate metabolic pathway; ASSOCIATED WITH BH4-deficient hyperphenylalaninemia A (ortholog); disease of metabolism (ortholog); Hyperphenylalaninemia, BH4-Deficient, due to Partial PTS Deficiency (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; cobalt dichloride]
Grid2	rgd:68368	[ENCODES a protein that exhibits identical protein binding; PDZ domain binding; scaffold protein binding (ortholog); INVOLVED IN regulation of presynapse assembly; cellular protein localization (ortholog); cerebellar granule cell differentiation (ortholog); PARTICIPATES IN long term depression; ASSOCIATED WITH autosomal recessive spinocerebellar ataxia 18 (ortholog); genetic disease (ortholog); schizophrenia (ortholog); FOUND IN glutamatergic synapse; integral component of postsynaptic density membrane; parallel fiber to Purkinje cell synapse; INTERACTS WITH 1,2-dimethylhydrazine; bisphenol A; chlorpyrifos]
Rab11b	rgd:68369	[ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); GTPase activity (ortholog); INVOLVED IN constitutive secretory pathway; regulated exocytosis; amyloid-beta clearance by transcytosis (ortholog); PARTICIPATES IN endocytosis pathway; vasopressin signaling pathway via receptor type 2; ASSOCIATED WITH autistic disorder (ortholog); human immunodeficiency virus infectious disease (ortholog); NEURODEVELOPMENTAL DISORDER WITH ATAXIC GAIT, ABSENT SPEECH, AND DECREASED CORTICAL WHITE MATTER (ortholog); FOUND IN anchored component of synaptic vesicle membrane; cytoplasmic vesicle; synaptic vesicle; INTERACTS WITH 9-cis-retinoic acid; ammonium chloride; bexarotene]
Hmx1	rgd:1304928	[ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription, DNA-templated (ortholog); ASSOCIATED WITH Craniofacial Abnormalities (ortholog); microphthalmia (ortholog); oculoauricular syndrome (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; bisphenol A]
Rubcnl	rgd:1304929	[ENCODES a protein that exhibits phosphatidylinositol-3-phosphate binding (ortholog); phosphatidylinositol-4-phosphate binding (ortholog); phosphatidylinositol-5-phosphate binding (ortholog); INVOLVED IN autophagosome maturation (ortholog); autophagosome-endosome fusion (ortholog); autophagosome-lysosome fusion (ortholog); ASSOCIATED WITH prostate cancer (ortholog); FOUND IN autophagosome membrane (ortholog); INTERACTS WITH bisphenol A; endosulfan; 17alpha-ethynylestradiol (ortholog)]
Dbil5	rgd:68360	[ENCODES a protein that exhibits fatty-acyl-CoA binding (inferred); lipid binding (inferred); INVOLVED IN spermatogenesis; FOUND IN cytoplasm (inferred)]
LOC102547626	rgd:7549984
Lxn	rgd:68361	[ENCODES a protein that exhibits metalloendopeptidase inhibitor activity (ortholog); INVOLVED IN detection of temperature stimulus involved in sensory perception of pain (ortholog); ASSOCIATED WITH Chromosomal Instability (ortholog); melanoma (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; acrylamide]
Lrat	rgd:68362	[ENCODES a protein that exhibits phosphatidylcholine-retinol O-acyltransferase activity; retinoic acid binding; retinol binding; INVOLVED IN response to retinoic acid; response to vitamin A; retinol metabolic process; PARTICIPATES IN altered retinoid cycle metabolic pathway; retinitis pigmentosa pathway; retinoic acid metabolic pathway; ASSOCIATED WITH breast ductal carcinoma (ortholog); celiac disease (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN intracellular membrane-bounded organelle; multivesicular body; perinuclear region of cytoplasm; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol]
LOC102552097	rgd:7726077
Hal	rgd:68363	[ENCODES a protein that exhibits histidine ammonia-lyase activity; INVOLVED IN histidine catabolic process (ortholog); PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); histidinemia (ortholog); FOUND IN cytosol (inferred); INTERACTS WITH (+)-alpha-tocopherol; (+)-schisandrin B; 1-naphthyl isothiocyanate]
Sigmar1	rgd:68364	[ENCODES a protein that exhibits opioid receptor activity; identical protein binding (ortholog); signaling receptor activity (ortholog); INVOLVED IN nervous system development; cell death in response to hydrogen peroxide (ortholog); protein homotrimerization (ortholog); ASSOCIATED WITH amnestic disorder (ortholog); amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 16 (ortholog); FOUND IN endoplasmic reticulum (ortholog); integral component of membrane (ortholog); nuclear envelope (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 3,3',5-triiodo-L-thyronine]
Cox7a2	rgd:68365	[ENCODES a protein that exhibits cytochrome-c oxidase activity (inferred); INVOLVED IN electron transport chain (inferred); proton transmembrane transport (inferred); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; FOUND IN mitochondrial respirasome (inferred); INTERACTS WITH ammonium chloride; ampicillin; bisphenol A]
Ubqln3	rgd:1304920	[PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH bisphenol A; bis(2-ethylhexyl) phthalate (ortholog); methotrexate (ortholog)]
Cdc27	rgd:1304921	[ENCODES a protein that exhibits protein phosphatase binding (ortholog); INVOLVED IN metaphase/anaphase transition of mitotic cell cycle (ortholog); protein K11-linked ubiquitination (ortholog); PARTICIPATES IN cell cycle pathway, mitotic; ubiquitin/proteasome degradation pathway; ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN anaphase-promoting complex (ortholog); centrosome (ortholog); cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acrylamide]
Irf2	rgd:1304922	[ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN defense response to virus (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of transcription, DNA-templated (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); focal adhesion (ortholog); nucleoplasm (ortholog); INTERACTS WITH 4-amino-2,6-dinitrotoluene; acrylamide; bisphenol A]
Batf	rgd:1304923	[ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to DNA damage stimulus (ortholog); cytokine production (ortholog); defense response to protozoan (ortholog); ASSOCIATED WITH intellectual disability (ortholog); ventricular septal defect (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 17beta-estradiol 3-benzoate; bis(2-ethylhexyl) phthalate; bisphenol A]
LOC102547943	rgd:7692197
Eme2	rgd:1304924	[ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN nucleic acid phosphodiester bond hydrolysis (inferred); ASSOCIATED WITH tuberous sclerosis 2 (ortholog); INTERACTS WITH bisphenol A; coumarin; toluene]