Terminology Service for NFDI4Health
All terms in UNIPROT
| Label | Id | Description |
|---|---|---|
| Repetin | P97347 | [Function: Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein.] |
| Nucleoredoxin | P97346 | [Function: Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A).] |
| UPF0575 protein C19orf67 | A6NJJ6 | |
| Serine/threonine-protein kinase Kist | P97343 | [Function: Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity).] |
| Transmembrane 6 superfamily member 2 | Q8R1J1 | [Function: Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content. May function as sterol isomerase.] |
| Cytoplasmic dynein 2 heavy chain 1 | Q45VK7 | [Function: May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis. According to PubMed:8666668, it may play a role in transport between endoplasmic reticulum and Golgi or organization of the Golgi in cells.] |
| Cytochrome c oxidase subunit 1 | P00395 | [Function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.] |
| Stromelysin-3 | P24347 | [Function: May play an important role in the progression of epithelial malignancies.] |
| Cytochrome c oxidase subunit 1 | P00397 | [Function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.] |
| Inactive polyglycylase TTLL10 | Q6ZVT0 | [Function: Inactive polyglycylase.] |
| COP9 signalosome complex subunit 9 | Q3U898 | [Function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Plays a role in cell proliferation.] |
| Ubiquitin-conjugating enzyme E2 E1 | P51965 | [Function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination.] |
| Probable methyltransferase-like protein 15 | Q9DCL4 | [Function: Probable S-adenosyl-L-methionine-dependent methyltransferase.] |
| 40S ribosomal protein SA | P38983 | [Function: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.] |
| Ecto-NOX disulfide-thiol exchanger 2 | Q8R0Z2 | [Function: May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 22 minutes and play a role in control of the ultradian cellular biological clock (By similarity).] |
| Myb-related protein A | P51960 | [Function: Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3' (PubMed:7813437, PubMed:23523368). Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism, such as PIWIL1 (PubMed:21750041, PubMed:23523368). The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity (PubMed:23523368).] |
| UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 | Q3TW96 | |
| Protein phosphatase inhibitor 2 | Q9DCL8 | [Function: Inhibitor of protein-phosphatase 1.] |
| Multifunctional protein ADE2 | Q9DCL9 | |
| Cytosolic 10-formyltetrahydrofolate dehydrogenase | Q8R0Y6 |