Terminology Service for NFDI4Health
All terms in UNIPROT
| Label | Id | Description |
|---|---|---|
| Four and a half LIM domains protein 1 | Q9WUH4 | [Function: May have an involvement in muscle development or hypertrophy. Isoform 2 binds to RBP-J and plays a negative regulatory role in the RBP-J-mediated transcription in mammalian systems (By similarity).] |
| LIM/homeobox protein Lhx9 | Q9WUH2 | [Function: Involved in gonadal development.] |
| Transmembrane protein 115 | Q9WUH1 | [Function: May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi.] |
| Semaphorin-4G | Q9WUH7 | [Function: Cell surface receptor for PLXNB2. May play a role in axon guidance.] |
| Vacuolar protein sorting-associated protein 53 homolog | Q5VIR6 | [Function: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).] |
| Olfactory receptor 2T8 | A6NH00 | [Function: Odorant receptor.] |
| Tripartite motif-containing protein 10 | Q9WUH5 | [Function: Seems to play an important role in erythropoiesis.] |
| Endoplasmic reticulum aminopeptidase 2 | Q6P179 | [Function: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.] |
| BICD family-like cargo adapter 1 | Q6ZP65 | [Function: Component of secretory vesicle machinery in developing neurons that acts as a regulator of neurite outgrowth. Regulates the secretory vesicle transport by controlling the accumulation of Rab6-containing secretory vesicles in the pericentrosomal region restricting anterograde secretory transport during the early phase of neuronal differentiation, thereby inhibiting neuritogenesis (By similarity).] |
| Death-associated protein 1 | P51397 | [Function: Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death.] |
| Xin actin-binding repeat-containing protein 2 | A4UGR9 | [Function: Protects actin filaments from depolymerization.] |
| 28S ribosomal protein S29, mitochondrial | P51398 | [Function: Involved in mediating interferon-gamma-induced cell death.] |
| Putative protein ATP11AUN | Q6ZP68 | |
| Cytochrome c oxidase subunit 7A2, mitochondrial | P14406 | [Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.] |
| Fumarate hydratase, mitochondrial | P14408 | [Function: Catalyzes the dehydration of L-malate to fumarate. Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by-product of the urea cycle and amino-acid catabolism (By similarity). Also plays a role in DNA repair by promoting non-homologous end-joining (NHEJ). In response to DNA damage and phosphorylation by PRKDC, translocates to the nucleus and accumulates at DNA double-strand breaks (DSBs): acts by catalyzing formation of fumarate, an inhibitor of KDM2B histone demethylase activity, resulting in enhanced dimethylation of histone H3 'Lys-36' (H3K36me2) (By similarity).] |
| Histone-lysine N-methyltransferase MECOM | P14404 | [Function: Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro. Probably catalyzes the monomethylation of free histone H3 in the cytoplasm which is then transported to the nucleus and incorporated into nucleosomes where SUV39H methyltransferases use it as a substrate to catalyze histone H3 'Lys-9' trimethylation. Likely to be one of the primary histone methyltransferases along with PRDM16 that direct cytoplasmic H3K9me1 methylation.] |
| PRAME family member 25 | A6NGN4 | |
| Insulin-like peptide INSL5 | Q9WUG6 | [Function: May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).] |
| 39S ribosomal protein L54, mitochondrial | Q6P161 | |
| Golgin subfamily A member 6-like protein 6 | A8MZA4 |