Terminology Service < Semantic Lookup Platform

All terms in UNIPROT

Label	Id	Description
Somatostatin receptor type 3	P32745	[Function: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.]
Pleckstrin homology-like domain family A member 1	Q9QZA1	[Function: Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.]
Acyl-coenzyme A synthetase ACSM4, mitochondrial	Q7TN78	[Function: Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (PubMed:12709059). Capable of activating medium-chain fatty acids with a preference for C6-12 fatty acids (PubMed:12709059).]
A-kinase anchor protein 7 isoform gamma	Q7TN79	[Function: Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium (By similarity).]
CD151 antigen	Q9QZA6	[Function: Essential for the proper assembly of the glomerular and tubular basement membranes in kidney.]
Orexin receptor type 2	P56719	[Function: Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding.]
Orexin receptor type 1	P56718	[Function: Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding.]
Oxygen-regulated protein 1	P56716	[Function: Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme.]
Oxygen-regulated protein 1	P56715	[Function: Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the correct orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme (By similarity).]
Plasma membrane calcium-transporting ATPase 4	Q64542	[Function: Calcium/calmodulin-regulated and magnesium-dependent enzyme that catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell (By similarity). By regulating sperm cell calcium homeostasis, may play a role in sperm motility (By similarity).]
Sodium/potassium-transporting ATPase subunit alpha-4	Q64541	[Function: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility.]
Coiled-coil domain-containing protein 179	H3BU77
Cytosolic iron-sulfur assembly component 3	Q7TMW6	[Function: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect (By similarity).]
Sodium-dependent proline transporter	Q6PGE7	[Function: Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals.]
Synaptotagmin-16	Q7TN83	[Function: May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent.]
Zinc finger protein 316	Q6PGE4	[Function: May be involved in transcriptional regulation.]
Synaptotagmin-14	Q7TN84	[Function: May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent.]
Regulator of G-protein signaling 16	P56700	[Function: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals.]
4-hydroxyphenylpyruvate dioxygenase	P32755	[Function: Key enzyme in the degradation of tyrosine.]
Copper-transporting ATPase 2	Q64535	[Function: Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.]