Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Kit Ligand	NCIT_C20440	[Kit ligand (273 aa, ~31 kDa) is encoded by the human KITLG gene. This protein is involved in melanogenesis, hematopoiesis and mast cell development, migration and function.]
Thrombopoietin	NCIT_C20441	[Thrombopoietin (353 aa, ~38 kDa) is encoded by the human THPO gene. This protein is involved in both megakaryocyte differentiation and platelet activation.]
HPV-Mediated (p16-Positive) Oropharyngeal Cancer cN1 TNM Finding v8	NCIT_C132873	[HPV-mediated (p16-positive) oropharyngeal cancer with metastasis in one or more ipsilateral lymph nodes, none larger than 6 cm. (from AJCC 8th Ed.)]
HPV-Mediated (p16-Positive) Oropharyngeal Cancer Clinical Regional Lymph Nodes TNM Finding v8	NCIT_C132872	[A clinical finding about one or more characteristics of HPV-mediated (p16-positive) oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.]
HPV-Mediated (p16-Positive) Oropharyngeal Cancer cN2 TNM Finding v8	NCIT_C132874	[HPV-mediated (p16-positive) oropharyngeal cancer with contralateral or bilateral lymph node metastasis, none larger than 6 cm. (from AJCC 8th Ed.)]
HPV-Mediated (p16-Positive) Oropharyngeal Cancer cN3 TNM Finding v8	NCIT_C132875	[HPV-mediated (p16-positive) oropharyngeal cancer with lymph node(s) metastasis, larger than 6 cm. (from AJCC 8th Ed.)]
HPV-Mediated (p16-Positive) Oropharyngeal Cancer Pathologic Distant Metastasis TNM Finding v8	NCIT_C132876	[A pathologic finding about one or more characteristics of HPV-mediated (p16-positive) oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.]
HPV-Mediated (p16-Positive) Oropharyngeal Cancer Pathologic TNM Finding v8	NCIT_C132859	[A pathologic finding about one or more characteristics of HPV-mediated (p16-positive) oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system.]
HPV-Mediated (p16-Positive) Oropharyngeal Cancer pM1 TNM Finding v8	NCIT_C132877	[HPV-mediated (p16-positive) oropharyngeal cancer with distant metastasis. (from AJCC 8th Ed.)]
HPV-Mediated (p16-Positive) Oropharyngeal Cancer Clinical Distant Metastasis TNM Finding v8	NCIT_C132878	[A clinical finding about one or more characteristics of HPV-mediated (p16-positive) oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to distant metastases.]
HPV-Mediated (p16-Positive) Oropharyngeal Cancer Clinical TNM Finding v8	NCIT_C132860	[A clinical finding about one or more characteristics of HPV-mediated (p16-positive) oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system.]
HPV-Mediated (p16-Positive) Oropharyngeal Cancer cM0 TNM Finding v8	NCIT_C132879	[HPV-mediated (p16-positive) oropharyngeal cancer without evidence of distant metastasis. (from AJCC 8th Ed.)]
Glial Cell Line-Derived Neurotrophic Factor	NCIT_C20446	[Glial cell line-derived neurotrophic factor (211 aa, ~24 kDa) is encoded by the human GDNF gene. This protein plays a role in the modulation of the survival and differentiation of dopaminergic neurons.]
Parathyroid Hormone-Related Protein	NCIT_C20447	[Parathyroid hormone-related protein (177 aa, ~20 kDa) is encoded by the human PTHLH gene. This protein plays a role in cell and organ growth, organ development, cell migration, cell differentiation and calcium ion transport.]
Platelet-Derived Growth Factor	NCIT_C20448	[A family of growth factors that act as potent mitogens and are involved in the stimulation of angiogenesis. There are four members of this family (platelet-derived growth factor A, B, C and D) that are characterized by a core motif of eight cysteines. They bind to their cognate receptor tyrosine kinases (platelet-derived growth factor receptor family) as homodimers or heterodimers to stimulate signaling.]
Platelet-Derived Growth Factor Subunit B	NCIT_C20449	[Platelet-derived growth factor subunit B (241 aa, ~27 kDa) is encoded by the human PDGFB gene. This protein is involved in the regulation of embryonic development, cell proliferation, cell migration, cell survival and chemotaxis.]
Insulin-Like Growth Factor	NCIT_C20442	[Bound to IGFBPs in the circulation, Insulin-Like Growth Factors (IGFs, Somatomedins) are a family of extracellular signaling peptides (potential autocrine ligands) involved in mediation of growth hormone action, stimulation of insulin action, and growth and development. The three main somatomedins are Somatomedin C (IGF1), Somatomedin A (IGF2), and Somatomedin B. Single chain IGFs I and II share about 47% amino acid homology with insulin (INS) and 31% with relaxin.]
Neurotrophin	NCIT_C20443
HPV-Mediated (p16-Positive) Oropharyngeal Cancer pN1 TNM Finding v8	NCIT_C132870	[HPV-mediated (p16-positive) oropharyngeal cancer with metastasis in four or fewer lymph nodes. (from AJCC 8th Ed.)]
HPV-Mediated (p16-Positive) Oropharyngeal Cancer Pathologic Regional Lymph Nodes TNM Finding v8	NCIT_C132867	[A pathologic finding about one or more characteristics of HPV-mediated (p16-positive) oropharyngeal cancer, following the rules of the TNM AJCC v8 classification system as they pertain to staging of regional lymph nodes.]