Terminology Service < Semantic Lookup Platform

All terms in NCIT

Label	Id	Description
Lymph Node Pain, CTCAE 5.0	NCIT_C146773	[A disorder characterized by a sensation of marked discomfort in a lymph node.]
Blood and Lymphatic System Disorders, CTCAE	NCIT_C143164
Carbohydrate Supplement Drink	NCIT_C107165	[A nutritional supplement drink containing 12.5% carbohydrates, which may enhance recovery following gastrointestinal (GI) surgery. Oral intake of the carbohydrate drink before surgery may prevent insulin resistance and associated hyperglycemia. It may also maintain adequate protein balance and muscle function. Ultimately, giving carbohydrates immediately before surgery may improve overall recovery time and return of GI function. It may also decrease muscle loss.]
Stomach Pain, CTCAE 5.0	NCIT_C146774	[A disorder characterized by a sensation of marked discomfort in the stomach.]
pBCAR3 Phosphopeptide-tetanus Peptide Vaccine	NCIT_C107166	[A vaccine composed of a phosphorylated peptide from the tumor associated antigen breast cancer anti-estrogen resistance-3 (BCAR3) and a tetanus-derived peptide, with potential immunomodulating and antineoplastic activities. Upon administration of pBCAR3 phosphopeptide-tetanus peptide vaccine, the pBCAR3 phosphopeptide may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against phosphopeptide-containing tumor cells. The tetanus peptide serves as an immunoadjuvant and induces a helper T-cell response, which may help stimulate an immune response against the pBCAR3-expressing melanoma tumor cells. BCAR3 is upregulated in a variety of cancer cells.]
Nystagmus, CTCAE 5.0	NCIT_C146775	[A disorder characterized by involuntary movements of the eyeballs.]
pIRS2 Phosphopeptide-tetanus Peptide Vaccine	NCIT_C107167	[A vaccine composed of a phosphorylated peptide from the tumor associated antigen insulin receptor substrate-2 (IRS2) and a tetanus-derived peptide, with potential immunomodulating and antineoplastic activities. Upon administration of pIRS2 phosphopeptide-tetanus peptide vaccine, the pIRS2 phosphopeptide may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against phosphopeptide-containing tumor cells. The tetanus peptide serves as an immunoadjuvant and induces a helper T-cell response which may help stimulate an immune response against the pIRS2-expressing melanoma tumor cells. IRS2 is upregulated in a variety of cancer cells.]
pBCAR3/pIRS2-Phosphopeptide-tetanus Peptide Vaccine	NCIT_C107168	[A vaccine composed of phosphorylated peptides from the tumor associated antigens breast cancer anti-estrogen resistance-3 (BCAR3) and insulin receptor substrate-2 (IRS2) and a tetanus-derived peptide, with potential immunomodulating and antineoplastic activities. Upon administration of pBCAR3/pIRS2 phosphopeptide-tetanus peptide vaccine, the pBCAR3/pIRS2 phosphopeptide may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing either phosphopeptide. The tetanus peptide serves as an immunoadjuvant and induces a helper T-cell response which may help stimulate an immune response against pBCAR3 and pIRS2-expressing melanoma tumor cells. BCAR3 and IRS2 are upregulated in a variety of cancer cells.]
NR1H3 wt Allele	NCIT_C132114	[Human NR1H3 wild-type allele is located in the vicinity of 11p11.2 and is approximately 21 kb in length. This allele, which encodes oxysterols receptor LXR-alpha protein, plays a role in both cholesterol homeostasis and the expression of retinoid-responsive genes.]
NR1H3 Gene	NCIT_C132113	[This gene is involved in the regulation of retinoid responses and cholesterol homeostasis.]
Oxysterols Receptor LXR-Alpha	NCIT_C132115	[Oxysterols receptor LXR-alpha (447 aa, ~50 kDa) is encoded by the human NR1H3 gene. This protein is involved in transcriptional regulation and cholesterol homeostasis.]
Liver X Receptor-Like Family	NCIT_C128275	[A nuclear receptor family that binds oxysterols or bile acids and, after forming a heterodimer with a member of the retinoid X receptor (RXR) family, modulates the expression of genes that are involved in cholesterol, fatty acid, and glucose homeostasis. The members of this family include oxysterols receptor LXR-alpha (NR1H3), oxysterols receptor LXR-beta (NR1H2) and bile acid receptor (NR1H4).]
NEK1 Gene	NCIT_C132116	[This gene plays a role in protein phosphorylation and the modulation of cilia assembly and cell division.]
NEK1 wt Allele	NCIT_C132117	[Human NEK1 wild-type allele is located in the vicinity of 4q33 and is approximately 219 kb in length. This allele, which encodes serine/threonine-protein kinase Nek1 protein, is involved in cell division, cilia assembly and protein phosphorylation. Mutation of the gene is associated with short-rib thoracic dysplasia 6 with or without polydactyly.]
Muscarinic Acetylcholine Receptor M3	NCIT_C20967	[Muscarinic acetylcholine receptor M3 (590 aa, ~66 kDa) is encoded by the human CHRM3 gene. This protein plays a role in both acetylcholine binding and smooth muscle contraction.]
Serine/Threonine-Protein Kinase Nek1	NCIT_C132118	[Serine/threonine-protein kinase Nek1 (1258 aa, ~143 kDa) is encoded by the human NEK1 gene. This protein plays a role in cilia assembly, protein phosphorylation and cell division.]
Centrosome	NCIT_C32285	[A small region of cytoplasm adjacent to the nucleus that contains the centrioles and serves to organize the microtubules.]
CHRM5 Gene	NCIT_C20968	[This gene plays a role in G protein-coupled receptor signal transduction, and may play a role in the regulation of cyclic AMP levels.]
Nasal Swab	NCIT_C132119	[A method used to collect biological material from within the nasal passages. A cotton swab is inserted into the nasal opening and rotated against the anterior nasal mucosa and them withdrawn.]
Muscarinic Acetylcholine Receptor M5	NCIT_C20969	[Muscarinic acetylcholine receptor M5 (532 aa, ~60 kDa) is encoded by the human CHRM5 gene. This protein plays a role in both acetylcholine binding and G protein-coupled receptor signaling.]